IRF2 antibody

Rabbit anti Human IRF2

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
IRF2

Product Code Applications Pack Size List Price Your Price Qty
AHP3077
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 0.1 ml loader
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loader
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Rabbit anti Human IRF2 antibody recognizes interferon regulatory factor 2.

IRF2 is a member of the interferon regulatory transcription factor (IRF) family and competitively inhibits the IRF1-mediated transcription of genes, including interferons alpha and beta. IRF2 has also been shown to act as a transcriptional activator of histone H4 (Harada et al. 1989).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to human IRF2 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.035% Sodium Azide (NaN3)
30% Glycerol
Carrier Free
Yes
Immunogen
A peptide within the C-terminal region of human IRF2
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/1000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
P14316
Entrez Gene
IRF2
GO Terms
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0005515 protein binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003702 RNA polymerase II transcription factor activity
GO:0007596 blood coagulation
GO:0005654 nucleoplasm
GO:0005925 focal adhesion
GO:0008283 cell proliferation
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060337 type I interferon-mediated signaling pathway
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products