HMGN2 antibody

Rabbit anti Human HMGN2

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
HMGN2

Product Code Applications Pack Size List Price Your Price Qty
AHP3076
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 0.1 ml loader
List Price Your Price
loader
Search for Batch Specific Datasheets

Rabbit anti Human HMGN2 antibody recognizes high mobility group nucleosome-binding domain-containing protein 2, also known as non-histone chromosomal protein HMG-17.

HMGN2 is a 9 kDa member of the HMG class of chromosomal proteins, the most abundant non-histones present in the nuclei of eukaryotic cells (Hock et al. 2007). Chromatin regions with high levels of HMGN2 are enriched in transcriptionally active genes and in acetylated histones. HMGN2 associates with actively transcribed genes. HMGN2 also binds to the inner side of the nucleosomal DNA, thereby regulating the interaction between the DNA and the nucleosome. HMGN2 may also play a role in maintaining transcribable genes in a unique chromatin conformation (Garza-Manero et al. 2019).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to human HMGN2 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.035% Sodium Azide (NaN3)
30% Glycerol
Carrier Free
Yes
Immunogen
A peptide within the N-terminal region of human HMGN2
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Description Product Code Applications Pack Size List Price Your Price Quantity
Goat anti Rabbit IgG (Fc):Biotin STAR121B E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):Biotin
Goat anti Rabbit IgG (Fc):FITC STAR121F F 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):FITC
Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):HRP
Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (H/L):HRP
Sheep anti Rabbit IgG:FITC STAR34B C F 1 mg loader
List Price Your Price
loader
Description Sheep anti Rabbit IgG:FITC
Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader
List Price Your Price
loader
Description Sheep anti Rabbit IgG:RPE

UniProt
P05204
Entrez Gene
HMGN2
GO Terms
GO:0005515 protein binding
GO:0000785 chromatin
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006325 chromatin organization
GO:0006355 regulation of transcription, DNA-dependent
Request a different product with this specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products