Glucose Transporter 5 antibody

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Rabbit anti Human Glucose Transporter 5

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product Code Applications Pack Size List Price Quantity
4670-1759
Datasheet
P WB
SDS
0.1 ml loader

Rabbit anti Human Glucose Transporter 5 antibody recognizes Solute carrier family 2, facilitated glucose transporter member 5, also known as the Glucose 5 transporter, "glucose transporter type 5, small intestine", GLUT5 or Fructose transporter. Glucose Transporter 5 catalyses the uptake of D-fructose into cells. Glucose Transporter 5 is a 501 amino acid ~55 kDa multiple pass transmembrane glycoprotein protein expressed in the plasma membrane and found mainly in intestinal tissue, kidney, and spermatozoa. (UniProt: P22732).

Increased intestinal levels of GLUT5 are seen in type 2 diabetes.

Product Details

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09%Sodium Azide (NaN3)
Immunogen
A synthetic peptide (ELKELPPVTSEQ) corresponding to the carboxy terminus of the human GLUT 5. To accomodate KLH conjugation a cysteine was added to the N-terminal.
Approx. Protein Concentrations
IgG concentration 5.0 mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee
12 months from date of despatch

More Information

UniProt
P22732
Entrez Gene
SLC2A5
GO Terms
GO:0005886 plasma membrane
GO:0016021 integral to membrane
GO:0005353 fructose transmembrane transporter activity
GO:0005355 glucose transmembrane transporter activity
GO:0005975 carbohydrate metabolic process
Regulatory
For research purposes only

Applications of Glucose Transporter 5 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/50 1/200
Western Blotting 1/150 1/500
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (Fc):Biotin STAR121B E WB 1 mg loader
Goat anti Rabbit IgG (Fc):FITC STAR121F F 1 mg loader
Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
Sheep anti Rabbit IgG:FITC STAR34B C F 1 mg loader
Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader
Sheep anti Rabbit IgG:DyLight®488 STAR36D488GA F IF WB 0.1 mg
Sheep anti Rabbit IgG:DyLight®680 STAR36D680GA F IF WB 0.1 mg
Sheep anti Rabbit IgG:Dylight®800 STAR36D800GA F IF WB 0.1 mg

Useful Reagents Available

Description Product Code Applications Pack Size List Price Quantity
Antigen Retrieval Buffer, pH8.0 BUF025A P 500 ml
Antigen Retrieval Buffer, pH8.0 BUF025C P 50 ml
TidyBlot Western Blot Detection Reagent:HRP STAR209P WB* 0.5 ml

Product Specific References

References for Glucose Transporter 5 antibody

  1. Mahraoui, L. et al. (1992) Expression and localization of GLUT-5 in Caco-2 cells, human small intestine, and colon.
    Am J Physiol. 263 (3 Pt 1): G312-8.