FLIP L antibody
Rabbit anti Human FLIP L (C-Terminal)
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- FLIP L
- Region
- (C-TERMINAL)
Rabbit anti Human FLIP L antibody recognizes the ~55 kDa FLIPL protein, a FLICE inhibitory protein. FLIP was cloned independently in a number of laboratories, and is also known as Casper, I-FLICE, FLAME-1, CASH and CLARP. FLIP has two death effector domains (DEDs) and a caspase-like domain. It interacts with FADD and caspase-8 and -10, potently inhibiting apoptosis by all known death receptors. FLIP exists in a short form (FLIPS) and a long form (FLIPL). Only FLIPL is recognised by Rabbit anti Human FLIP L antibody (AHP430). |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to FLIP were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.02% Sodium Azide - Immunogen
- Peptide at C-terminus of human FLIPL.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunohistology - Frozen | |||
Western Blotting | 1/500 | 1/2000 |
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References for FLIP L antibody
-
Zhang, J. et al. (2001) Impaired Fas signaling pathway is involved in defective T cell apoptosis in autoimmune murine arthritis.
J Immunol. 166 (8): 4981-6.
Further Reading
-
Irmler, M. et al. (1997) Inhibition of death receptor signals by cellular FLIP.
Nature. 388 (6638): 190-5.
AHP430
040214 164760If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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