DMAP1 antibody

Rabbit anti Human DMAP1

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
DMAP1

Product Code Applications Pack Size List Price Your Price Qty
AHP3037
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
IP WB 0.1 ml loader
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loader
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Rabbit anti Human DMAP1 antibody recognizes DNA methyltransferase 1-associated protein 1, also known as DNMT1-associated protein 1.

DMAP1 is a 52 kDa enzyme that functions as a subunit of several complexes involved in the repression or activation of transcription. As a component of the nucleosome acetyltransferase of H4 complex, DMAP1 interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. DMAP1 can also repress transcription independently through direct interaction with DNA methyltransferase 1 (Rountree et al. 2000) (Xin et al. 2004).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to human DMAP1 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.035% Sodium Azide (NaN3)
30% Glycerol
Carrier Free
Yes
Immunogen
A peptide within the C-terminal region of human DMAP1
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunoprecipitation 10 µl per IP
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
Q9NPF5
Entrez Gene
DMAP1
GO Terms
GO:0005515 protein binding
GO:0003677 DNA binding
GO:0006306 DNA methylation
GO:0016564 transcription repressor activity
GO:0035267 NuA4 histone acetyltransferase complex
GO:0040008 regulation of growth
GO:0043967 histone H4 acetylation
GO:0043968 histone H2A acetylation
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products