CD257 antibody

Rabbit anti Human CD257

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
CD257

Product Code Applications Pack Size List Price Your Price Qty
AHP587
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
IC WB 0.1 mg loader
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loader
Search for Batch Specific Datasheets

Rabbit anti Human CD257 antibody recognizes CD257, also known as BLyS, BAFF, TALL-1 and THANK. CD257 is a member of the tumor necrosis factor (TNF) superfamily. CD257 and its receptor TACI/BCMA are involved in the development of autoimmune diseases. CD257 activates NFκB and JNK (c-jun N-terminal kinase) inducing apoptosis.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antisera to CD257 (BAFF) were raised by repeated immunisation of rabbit with highly purified antigen. Purified IgG was prepared from whole serum by ion exchange chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02%Sodium Azide
Immunogen
Peptide corresponding to amino acids 254-269 of human CD257 (BAFF).
Approx. Protein Concentrations
IgG concentration 1 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunocytochemistry 1ug/ml
Western Blotting 0.25ug/ml 1ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
AHP587 detects a band of approximately 31kDa in mouse spleen tissue lysate and human HL60 cell lysate

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Further Reading

  1. Moore, P.A. et al. (1999) BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator.
    Science. 285 (5425): 260-3.

Synonyms
BAFF
BLyS
RRID
AB_2256330
UniProt
Q9Y275
Entrez Gene
TNFSF13B
GO Terms
GO:0005886 plasma membrane
GO:0016021 integral to membrane
GO:0007165 signal transduction
GO:0005125 cytokine activity
GO:0005164 tumor necrosis factor receptor binding
GO:0005615 extracellular space
GO:0005625 soluble fraction
GO:0006955 immune response
GO:0008283 cell proliferation
View more products with CD257 specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products