CD195 antibody
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P WB ResetRabbit anti Human CD195 (CCR5)
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- CD195
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| Rabbit anti Human CD195 antibody recognizes the N-terminal region of the chemokine receptor CCR5, also known as CD195. CCR5 is a receptor for the beta chemokines RANTES, MIP-1alpha and MIP-1beta. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to CCR5 was raised by repeated immunization of rabbit with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.02% Sodium Azide - Immunogen
- Peptide corresponding to amino acids 6 to 20 of human CCR5.
- Approx. Protein Concentrations
- IgG concentration 1 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunohistology - Paraffin 1 |  |
20 ug/ml | |
| Western Blotting | |
1/1000 |
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Histology Positive Control Tissue
- Human lymph node.
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References for CD195 antibody
-
Mi, Z. et al. (2011) Osteopontin Promotes CCL5-Mesenchymal Stromal Cell Mediated Breast Cancer Metastasis.
Carcinogenesis. 32: 477-87. -
Ghosh, R. et al. (2013) Study of CC chemokine receptor 5 in renal allograft rejection.
Indian J Nephrol. 23: 196-200.
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