CD126/Il-6R antibody
Rabbit anti CD126/Il-6R
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- CD126/Il-6R
Rabbit anti CD126/IL-6R antibody recognizes CD126/IL-6R, also known as interleukin-6 receptor subunit alpha. CD126/IL-6R is a member of the type I cytokine receptor family. CD126/IL-6R binds to IL-6, the IL-6/IL-6R complex then associates with two molecules of interleukin 6 signal transducer (IL6ST), leading to signaling via the JAK/STAT pathway. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to CD126/IL-6R was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.05% ProClin 300
50% Glycerol - Immunogen
- Recombinant human CD126/IL-6R
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- ProClin is a trademark of The Dow Chemical Company (“Dow”) or an affiliated company of Dow.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Western Blotting | 1/500 | 1/2000 |
- Western Blotting
- Rabbit anti CD126/IL-6R antibody detects a band of approximately 52 kDa in cell lysates under reducing conditions
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Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml | Log in | |||
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TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB * | 0.5 ml | Log in | |||
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Description | TidyBlot Western Blot Detection Reagent:HRP |
- UniProt
- P08887
- Entrez Gene
- IL6R
- GO Terms
- GO:0002384 hepatic immune response
- GO:0002446 neutrophil mediated immunity
- GO:0002548 monocyte chemotaxis
- GO:0002690 positive regulation of leukocyte chemotaxis
- GO:0006953 acute-phase response
- GO:0005615 extracellular space
- GO:0005896 interleukin-6 receptor complex
- GO:0050830 defense response to Gram-positive bacterium
- GO:0050829 defense response to Gram-negative bacterium
- View More GO Terms
- GO:0010536 positive regulation of activation of Janus kinase activity
- GO:0016323 basolateral plasma membrane
- GO:0016324 apical plasma membrane
- GO:0042981 regulation of apoptosis
- GO:0019899 enzyme binding
- GO:0031018 endocrine pancreas development
- GO:0032717 negative regulation of interleukin-8 production
- GO:0032722 positive regulation of chemokine production
- GO:0032755 positive regulation of interleukin-6 production
- GO:0032966 negative regulation of collagen biosynthetic process
- GO:0034097 response to cytokine stimulus
- GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein
- GO:0042803 protein homodimerization activity
- GO:0043410 positive regulation of MAPKKK cascade
- GO:0045669 positive regulation of osteoblast differentiation
- GO:0045768 positive regulation of anti-apoptosis
- GO:0048661 positive regulation of smooth muscle cell proliferation
- GO:0070102 interleukin-6-mediated signaling pathway
- GO:0070119 ciliary neurotrophic factor binding
- GO:0070120 ciliary neurotrophic factor-mediated signaling pathway
AHP2449
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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