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BMP-9 antibody

Product Code Applications Pack Size List Price Your Price Qty
1406-1460
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E IF P WB 1 ml loader
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loader

Rabbit anti Human BMP-9 antibody recognizes Human BMP9 (Bone Morphogenic Protein), a member of the TGF-beta superfamily.

BMPs act through binding with a receptor complex consisting of type I and type II serine/threonine kinases, resulting ultimately in the activation of the Smad protein and mitogen-activated protein kinase (MAPK) signaling pathways. Several antagonist proteins, including, noggin, chordin, gremlin and follistatin, are responsible for modulating the signaling effects of BMPs, through the binding and blocking of receptor ligands, thereby preventing activation.

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09%Sodium Azide (NaN3)
Immunogen
Synthetic peptide corresponding to the amino acids 87 - 98 (CKDDMGVPTLKYH) of the native molecule conjugated to keyhole limpet haemocyanin.
Approx. Protein Concentrations
5.0mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/2000 1/20000
Immunofluorescence
Immunohistology - Paraffin
Western Blotting
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

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References for BMP-9 antibody

  1. (2011) Human Protein Atlas: CAB023357
    Human Protein Atlas: CAB023357

Immunohistology - Paraffin

Western Blotting

Synonyms
Growth Differentiation Factor 2
RRID
AB_2111086
UniProt
Q9UK05
Entrez Gene
GDF2
GO Terms
GO:0005125 cytokine activity
GO:0005615 extracellular space
GO:0040007 growth
GO:0008083 growth factor activity
GO:0010596 negative regulation of endothelial cell migration
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0030308 negative regulation of cell growth
GO:0030509 BMP signaling pathway
GO:0032924 activin receptor signaling pathway
GO:0045941 positive regulation of transcription
GO:0060389 pathway-restricted SMAD protein phosphorylation

1406-1460

1603 165780 1804

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