BMP-10 antibody
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Rabbit anti Human BMP-10
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- BMP-10
Antibody Quality and Performance Guarantee
| Rabbit anti Human BMP-10 antibody recognizes BMP-10, also known as Bone Morphogenetic Protein 10, a member of the TGF-β superfamily of proteins. With the exception of BMP-1, Bone Morphogenetic Proteins are growth factors orchestrating tissue architecture throughout the body. BMP-10 is a cardiac growth factor which expression is restricted to the heart where it plays a crucial role in the control of cardiac development, growth and maturation. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rat Expected from Sequence Mouse Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- Synthetic peptide corresponding to the amino acids 84 - 94 (LDKGVVTYKFK ) of human BMP-10 (402-412 of the unprocessed precursor) conjugated to Keyhole Limpet Haemocyanin. This sequence is identical to the published sequences for human, mouse and rat BMP-10 proteins.
- Approx. Protein Concentrations
- IgG concentration 5.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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| Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
| Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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| Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
| Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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| Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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| List Price | Your Price | ||||||
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| Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
| Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
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| List Price | Your Price | ||||||
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| Description | Sheep anti Rabbit IgG:FITC | ||||||
| Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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| List Price | Your Price | ||||||
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| Description | Sheep anti Rabbit IgG:RPE | ||||||
- RRID
- AB_2065657
- UniProt
- O95393
- Entrez Gene
- BMP10
- GO Terms
- GO:0005125 cytokine activity
- GO:0005615 extracellular space
- GO:0007219 Notch signaling pathway
- GO:0007512 adult heart development
- GO:0008083 growth factor activity
- GO:0009986 cell surface
- GO:0010596 negative regulation of endothelial cell migration
- GO:0010613 positive regulation of cardiac muscle hypertrophy
- GO:0010614 negative regulation of cardiac muscle hypertrophy
- View More GO Terms
- GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
- GO:0030018 Z disc
- GO:0030308 negative regulation of cell growth
- GO:0030509 BMP signaling pathway
- GO:0032924 activin receptor signaling pathway
- GO:0033612 receptor serine/threonine kinase binding
- GO:0045214 sarcomere organization
- GO:0045941 positive regulation of transcription
- GO:0055009 atrial cardiac muscle tissue morphogenesis
- GO:0055010 ventricular cardiac muscle tissue morphogenesis
- GO:0055015 ventricular cardiac muscle cell development
- GO:0060038 cardiac muscle cell proliferation
- GO:0060045 positive regulation of cardiac muscle cell proliferation
- GO:0060347 heart trabecula formation
- GO:0060389 pathway-restricted SMAD protein phosphorylation
1406-1560
0113R
156282
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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