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BMP-10 antibody

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Rabbit anti Human BMP-10

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
BMP-10

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Technical Suppport
Product Code Applications Pack Size List Price Your Price Qty
1406-1560
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E 1 ml loader
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loader
Search for Batch Specific Datasheets

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Rat Expected from Sequence
Mouse Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Synthetic peptide corresponding to the amino acids 84 - 94 (LDKGVVTYKFK ) of human BMP-10 (402-412 of the unprocessed precursor) conjugated to Keyhole Limpet Haemocyanin. This sequence is identical to the published sequences for human, mouse and rat BMP-10 proteins.
Approx. Protein Concentrations
IgG concentration 5.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

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RRID
AB_2065657
UniProt
O95393
Entrez Gene
BMP10
GO Terms
GO:0005125 cytokine activity
GO:0005615 extracellular space
GO:0007219 Notch signaling pathway
GO:0007512 adult heart development
GO:0008083 growth factor activity
GO:0009986 cell surface
GO:0010596 negative regulation of endothelial cell migration
GO:0010613 positive regulation of cardiac muscle hypertrophy
GO:0010614 negative regulation of cardiac muscle hypertrophy
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0030018 Z disc
GO:0030308 negative regulation of cell growth
GO:0030509 BMP signaling pathway
GO:0032924 activin receptor signaling pathway
GO:0033612 receptor serine/threonine kinase binding
GO:0045214 sarcomere organization
GO:0045941 positive regulation of transcription
GO:0055009 atrial cardiac muscle tissue morphogenesis
GO:0055010 ventricular cardiac muscle tissue morphogenesis
GO:0055015 ventricular cardiac muscle cell development
GO:0060038 cardiac muscle cell proliferation
GO:0060045 positive regulation of cardiac muscle cell proliferation
GO:0060347 heart trabecula formation
GO:0060389 pathway-restricted SMAD protein phosphorylation
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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