BAZ2A antibody

Rabbit anti Human BAZ2A

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
BAZ2A

Product Code Applications Pack Size List Price Your Price Qty
AHP3029
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SDS Safety Datasheet SDS
WB 0.1 ml loader
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loader
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Rabbit anti Human BAZ2A antibody recognizes bromodomain adjacent to zinc finger domain protein 2A, also known as transcription termination factor I-interacting protein 5 or hWALp3.

BAZ2A is an essential component of the NoRC (nucleolar remodeling complex) complex. This complex mediates the silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, which leads to heterochromatin formation and transcriptional silencing (Strohner et al. 2004).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to human BAZ2A was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.035% Sodium Azide (NaN3)
30% Glycerol
Carrier Free
Yes
Immunogen
A peptide within the N-terminal region of human BAZ2A
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/1000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
Q9UIF9
Entrez Gene
BAZ2A
GO Terms
GO:0000183 chromatin silencing at rDNA
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0005677 chromatin silencing complex
GO:0005730 nucleolus
GO:0006306 DNA methylation
GO:0006338 chromatin remodeling
GO:0006350 transcription
GO:0008270 zinc ion binding
GO:0016575 histone deacetylation
GO:0016922 ligand-dependent nuclear receptor binding
GO:0030528 transcription regulator activity
GO:0033553 rDNA heterochromatin
GO:0070577 histone acetyl-lysine binding
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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