ACTL6B antibody

Rabbit anti Human ACTL6B

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
ACTL6B

Product Code Applications Pack Size List Price Your Price Qty
AHP3025
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SDS Safety Datasheet SDS
WB 0.1 ml loader
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loader
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Rabbit anti Human ACTL6B antibody recognizes actin-like protein 6B.

ACTL6B is is a member of a family of actin-related proteins (ARPs). ARPs are involved in a number of cellular processes, including chromatin remodelling, vesicular transport, and nuclear migration. ACTL6B is important for c-Myc oncogenic activity (Park et al. 2002). ACTL6B is a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is thought regulate expression of genes in brain tissue via structural remodelling of their chromatin (Marcum et al. 2020).

Rabbit anti Human ACT6B antibody detects a band of 50 kDa.

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to human ACTL6B was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.035% Sodium Azide (NaN3)
30% Glycerol
Carrier Free
Yes
Immunogen
A peptide within the N-terminal region of human ACTL6B
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/250 1/500
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
O94805
Entrez Gene
ACTL6B
GO Terms
GO:0005515 protein binding
GO:0005200 structural constituent of cytoskeleton
GO:0005524 ATP binding
GO:0006350 transcription
GO:0007399 nervous system development
GO:0016514 SWI/SNF complex
GO:0016568 chromatin modification
GO:0045449 regulation of transcription
GO:0071565 nBAF complex
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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