IL-17A antibody

Rabbit anti Dog Interleukin-17A

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
IL-17A

Product Code Applications Pack Size List Price Your Price Qty
AHP2982
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E WB 0.1 mg loader
List Price Your Price
loader
Search for Batch Specific Datasheets

Rabbit anti Dog interleukin-17A antibody recognizes canine interleukin-17A (IL-17A), a 35 kDa disulfide-linked homodimer consisting of two 155 amino acid chains, which belongs to the IL-17 family (classified as IL-17A to IL-17F), and signals through the IL-17 receptor (IL-17R/CDw217).

IL-17, originally thought to have been produced primarily by activated CD4+ T cells, appears to have a range of cellular origins and induces a variety of target cells to secrete inflammatory cytokines, including IL-1β, IL-6, TNFα, IFNγ and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists.

Target Species
Dog
Species Cross-Reactivity
Target SpeciesCross Reactivity
Human
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antisera to canine interleukin-17A were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Recombinant canine interleukin-17A
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1ug/ml 5ug/ml
Western Blotting 0.1ug/ml 2ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
ELISA
This product may be used as a capture antibody in a sandwich ELISA together with AHP2982B as the detection reagent. Recombinant bovine interleukin-17A (PDP016 ) may be used as a standard.

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UniProt
C6L8D7
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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