Rabbit anti Streptococcus A antibody recognizes a type specific carbohydrate of group A Streptococcus (GAS) and does not react with other streptococci groups.
GAS are non-motile, non-spore forming bacteria that exist in pairs or as short chains. They are responsible for most cases of streptococcal illnesses including sore throat (strep thoat), scarlet fever and necrotizing fasciitis. The individual organisms are spheric in shape with a diameter of 0.6-1 mm. They produce 2 major classes of protein antigens: M antigens and T antigens of which the M protein is the major virulence factor.S. pyogenes is the only member of the Lancefield Group A Streptococci.
- Target Species
- Product Form
- Purified Ig - liquid
- Purified Ig prepared by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Streptococci, group A
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Streptococcus A antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
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Secondary Antibodies Available
Product Specific References
References for Streptococcus A antibody
Blom, A.M. et al. (2017) Factor H-IgG Chimeric Proteins as a Therapeutic Approach against the Gram-Positive Bacterial Pathogen Streptococcus pyogenes.
J Immunol. Oct 30 [Epub ahead of print].