Neisseria Meningitidis antibody

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Rabbit anti Neisseria Meningitidis

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product Code Applications Pack Size List Price Quantity
6600-5906
Datasheet
E IF
MSDS
1 ml loader

Rabbit anti Neisseria meningitidis antibodyreacts with Neisseria meningitidis serogroups A, B and C recognizing multiple antigens. Other serogroups have not been tested.

N. meningitidis is a gram-negative bacteria that is a causative agent of meningitis. There are 13 known significant serogroups, classified according to the structure of their polysaccharide capsule. Serogroups, A, B, C, D, X, Y, Z, 29E and W135 are responsible for virtually all cases of the human disease.

The carbohydrate component of the capsular membrane induces a T cell independent immune response, so neither long term immunity by memory cell formation nor antibody affinity maturation is observed. Rather than being engulfed and processed by an antigen presenting cell, the carbohydrate capsule interacts directly with B cells. This interaction causes production of serogroup specific antibodies, primarily IgM. IgG is also produced with an IgG1 response predominating in children and an IgG2 response predominating in adults.

Product Details

Target Species
Bacterial
Product Form
Purified IgG - liquid
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.1% Sodium Azide (NaN3)
Immunogen
Whole cell preparation of N. meningitidis types A, B and C.
Approx. Protein Concentrations
IgG concentration 4 mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee
18 months from date of despatch.

More Information

Regulatory
For research purposes only

Applications of Neisseria Meningitidis antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Immunofluorescence
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Sheep anti Rabbit IgG:Biotin 2AB02B C E P WB 1 ml loader
Goat anti Rabbit IgG (Fc):Biotin STAR121B E WB 1 mg loader
Goat anti Rabbit IgG (Fc):FITC STAR121F F 1 mg loader
Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
Sheep anti Rabbit IgG:FITC STAR34B C F 1 mg loader
Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader
Sheep anti Rabbit IgG:DyLight®488 STAR36D488GA F IF WB 0.1 mg
Sheep anti Rabbit IgG:DyLight®680 STAR36D680GA F IF WB 0.1 mg
Sheep anti Rabbit IgG:Dylight®800 STAR36D800GA F IF WB 0.1 mg

Product Specific References

References for Neisseria Meningitidis antibody

  1. Connor, D.O. et al. (2017) Epitope determination of immunogenic proteins of Neisseria gonorrhoeae.
    PLoS One. 12 (7): e0180962.