Cholera Toxin antibody

Rabbit anti Cholera Toxin Beta

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Cholera Toxin
Region
BETA

Product Code Applications Pack Size List Price Your Price Qty
2060-0020
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E ID 1 ml loader
List Price Your Price
loader
Search for Batch Specific Datasheets

Rabbit anti cholera toxin beta antibody recognizes the beta subunit of cholera toxin.

The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.

Target Species
Bacterial
Product Form
Purified Ig - liquid
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.1% Sodium Azide (NaN3)
Immunogen
Purified choleragenoid.
Approx. Protein Concentrations
4.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Immunodiffusion
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

Description Product Code Applications Pack Size List Price Your Price Quantity
Goat anti Rabbit IgG (Fc):Biotin STAR121B E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):Biotin
Goat anti Rabbit IgG (Fc):FITC STAR121F F 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):FITC
Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):HRP
Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (H/L):HRP
Sheep anti Rabbit IgG:FITC STAR34B C F 1 mg loader
List Price Your Price
loader
Description Sheep anti Rabbit IgG:FITC
Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader
List Price Your Price
loader
Description Sheep anti Rabbit IgG:RPE

References for Cholera Toxin antibody

  1. Thangawng, A.L. et al. (2010) A hard microflow cytometer using groove-generated sheath flow for multiplexed bead and cell assays.
    Anal Bioanal Chem. 398: 1871-81.
  2. Becker, P.M. et al. (2010) Inhibition of binding of the AB5-type enterotoxins LT-I and cholera toxin to ganglioside GM1 by galactose-rich dietary components.
    Foodborne Pathog Dis. 7: 225-33.

Flow Cytometry

RRID
AB_619362
UniProt
P01556
GO Terms
GO:0016020 membrane
GO:0006471 protein ADP-ribosylation
GO:0009405 pathogenesis
GO:0020002 host cell plasma membrane
GO:0031640 killing of cells of other organism
GO:0046812 host cell surface binding
View more products with Cholera Toxin specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Bacterial Products