MHC Class II H-2I-Ak/D/B/Q/R antibody | ER-TR3
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Rat anti Mouse MHC Class II H-2I-Ak/D/B/Q/R
- Product Type
- Monoclonal Antibody
- MHC Class II H-2I-Ak/D/B/Q/R
|Rat anti Mouse MHC Class II H-2I-Ak/D/B/Q/R antibody, clone ER-TR3 recognizes a polymorphic determinant of the mouse H-2I-A MHC class II antigen, reacting with haplotypes k, d, b, q and r. Mouse strains with the haplotypes s and f are not recognized by this antibody.
Mouse MHC class II antigens are expressed by dendritic cells, B cells and macrophages. In thymus tissues, clone ER-TR3 stains cortical and medullary stromal cells.
The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the H-2 region.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% sodium azide (NaN3)
- Carrier Free
- Isolated C3H thymic stromal cells.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Cells from immunised rats were fused with cells of the mouse P3-X63-Ag8.563 myeloma cell line.
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Frozen|
- Flow Cytometry
- Use 10μl of the suggested working dilution to label 106 cells in 100μl
Van Vliet, E. et al. (1984) Monoclonal antibodies to stromal cell types of the mouse thymus.
Eur J Immunol. 14 (6): 524-9.
References for MHC Class II H-2I-Ak/D/B/Q/R antibody
Huiskamp, R. et al. (1985) Repopulation of the mouse thymus after sublethal fission neutron irradiation. II. Sequential changes in the thymic microenvironment.
J Immunol. 134 (4): 2170-8.
Van Vliet, E. et al. (1985) Stromal cell types in the developing thymus of the normal and nude mouse embryo.
Eur J Immunol. 15 (7): 675-81.
Matsuno, K. et al. (2002) Kupffer cell-mediated recruitment of dendritic cells to the liver crucial for a host defense.
Dev Immunol. 9 (3): 143-9.
Gadagkar, S.G. et al. (2023) CD36 neutralisation blunts TLR2-IRF7 but not IRF3 pathway in neonatal mouse brain and immature human microglia following innate immune challenge.
Sci Rep. 13 (1): 2304.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"View all Anti-Mouse Products
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