STAT1 antibody | P02-5B7

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Mouse anti STAT1

Product Type
PrecisionAb Monoclonal
Product Code Applications Pack Size List Price Quantity
100 µl loader

Mouse anti STAT1 antibody recognizes signal transducer and activator of transcription 1-alpha/beta (STAT1) also known as transcription factor ISGF-3 components p91/p84. STAT1 is part of the transcription factor STAT family of proteins.

Members of the STAT family respond to cytokines and growth factors and are phosphorylated by receptor associated kinases to form homo- or hetero-dimers. These then translocate to the cell nucleus to act as transcription activators. STAT1 is activated by a number of different ligands including the interferon, gp130 and receptor tyrosine kinase families (Gerhartz et al. 1996). Mutations in the STAT1 gene lead to a number of immunological disorders including severe combined immunodeficiency phenotypes (Sharfe et al. 2014), or more selective immunodeficiencies to macrophagic (usually mycobacteria) bacteria, viruses or fungi depending on the mutation or abnormality involved (Boisson-Dupuis et al. 2012).

Product Details

Target Species
Western Blotting
Mouse anti STAT1 antibody detects bands of approximately 86 kDa and 92 kDa in HeLa cells
Product Form
Purified IgG - liquid
Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Peptide, aa 689-710 (EPMELDGPKGTGYIKTELISVS) of human STAT1
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml

Storage Information

Store undiluted at -20oC, avoiding repeated freeze thaw cycles
12 months from date of despatch

More Information

Entrez Gene
PrecisionAb is a trademark of Bio-Rad Laboratories
For research purposes only

Applications of STAT1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/5000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml

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