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MELAN-A antibody | RM333

Rabbit anti MELAN-A

Product Type
Monoclonal Antibody
Clone
RM333
Isotype
IgG
Specificity
MELAN-A

Product Code Applications Pack Size List Price Your Price Qty
MCA6347
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
P WB 0.1 ml loader
List Price Your Price
loader

Rabbit anti MELAN-A antibody recognizes melanoma antigen recognized by T-cells 1, also known as MLANA and MART-1.

MELAN-A is a human tumor-associated antigen expressed in healthy melanocytes and malignant melanoma. It is recognized by CD8+ T cells (Romero et al. 2014). More specifically, MELAN-A is a glycoprotein associated with the melanosome, an organelle in which melanin is synthesized (Song et al. 2009). Epitopes of MELAN-A have been used in melanoma immunotherapy protocols to enhance responses from cytotoxic T lymphocytes (Bioley et al. 2006).

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A from animal origin-free culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
1% Bovine Serum Albumin
50% Glycerol
Immunogen
A peptide corresponding to the N-terminus of human MELAN-A
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20°C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/500 1/1000
Western Blotting 1/500 1/1000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
Q16655
Entrez Gene
MLANA
GO Terms
GO:0005515 protein binding
GO:0005887 integral to plasma membrane
GO:0005789 endoplasmic reticulum membrane
GO:0005802 trans-Golgi network
GO:0042470 melanosome

MCA6347

157612

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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