IL-7 antibody | BVD10-40F6
Rat anti Human Interleukin-7
- Product Type
- Monoclonal Antibody
- Clone
- BVD10-40F6
- Isotype
- IgG1
- Specificity
- IL-7
Antibody Quality and Performance Guarantee
| Rat anti Human Interleukin-7 antibody, clone BVD10-40F6 recognizes human interleukin 7 (IL-7), also known as Lymphopoietin 1 or pre-B cell factor. IL-7 is a 177 amino acid haematopoietic growth factor stimulating primarily early B and T lymphocytes. IL- 7 is required for development of T-cells in the thymus (Plum et al. 1996) and absence of the IL-7 receptor α chain (CD127) leads to a severe combined immunodeficiency condition through the lack of T-cell production (Roifman et al. 2000). IL-7 is also important post-thymically for homeostasis of naive T-cell populations and generation and survival of CD4+ memory T-cells (Kondrack et al. 2003). IL-7 deficiency or deficient function is also noted in immunodeficiency diseases including rheumatoid arthritis (Leonard 2005), chronic colitis (Totsuka et al. 2007). Multiple sclerosis through CD127 (Svejgaard 2008) and diabetes (Li et al. 2011). Rat anti Human Interleukin-7 antibody, clone BVD10-40F6 has been used successfully in the development of a sensitive ELISA assay as a capture reagent for human IL-7. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Antibody purified from tissue culture supernatant
- Buffer Solution
- Borate buffered saline
- Preservative Stabilisers
- None present
- Approx. Protein Concentrations
- 0.5 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- Guaranteed for 12 months from the date of despatch or until the date of expiry, whichever comes first. Please see label for expiry date.
Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- RRID
- AB_2125814
- UniProt
- P13232
- Entrez Gene
- IL7
- GO Terms
- GO:0005125 cytokine activity
- GO:0005139 interleukin-7 receptor binding
- GO:0005615 extracellular space
- GO:0006959 humoral immune response
- GO:0007267 cell-cell signaling
- GO:0009887 organ morphogenesis
- GO:0008083 growth factor activity
- GO:0030890 positive regulation of B cell proliferation
- GO:0045453 bone resorption
- View More GO Terms
- GO:0045582 positive regulation of T cell differentiation
1012201
155176
157198
165848
166678
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
View more products with IL-7 specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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