IgG antibody | R10Z8E9


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E ResetMouse anti Human IgG (CH2 Domain)
- Product Type
- Monoclonal Antibody
- Clone
- R10Z8E9
- Isotype
- IgG1
- Specificity
- IgG
- Region
- (CH2 Domain)
Mouse anti Human IgG (CH2 Domain), clone R10Z8E9 recognizes Human IgG. Clone R10Z8E9 appears to be specific to Human IgG and been demonstrated by ELISA not to recognize IgG from non-human primate species (Baboon, Marmoset, Rhesus and Cynomologus macaques), nor does it recognize mouse or rat immunoglobulin. NB: This reagent may not be used for the detection of therapeutic antibodies from samples obtained from experimental animals without prior consent by the owner of EP 1 853 921 (F. Hoffmann-La Roche AG, Basel, Switzerland) and /or US 7,955,806 (HOFFMANN-LA ROCHE, INC., Nutley, NJ). View a summary of anti-human IgG Fc specific antibodies for the detection of therapeutic antibodies. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat Cynomolgus monkey Baboon Marmoset Rhesus Monkey - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Carrier Free
- Yes
- Immunogen
- Polyclonal Human IgG
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Fusion Partners
- Spleen cells from immunized BALB/c mice were fused with cells of the NS0 myeloma cell line.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Licensed Use
- Not for the detection of therapeutic antibodies from samples obtained from experimental animals without prior consent by the owner of EP 1 853 921 (F. Hoffmann-La Roche AG, Basel, Switzerland) and /or US 7,955,806 (HOFFMANN-LA ROCHE, INC., Nutley, NJ)
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | ![]() |
- ELISA
- This product is suitable for use in indirect ELISA applications.
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Goat anti Mouse IgG (H/L):HRP (Multi Species Adsorbed) | STAR117P | C E WB | 0.5 mg |
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List Price | Your Price | ||||||
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Description | Goat anti Mouse IgG (H/L):HRP (Multi Species Adsorbed) | ||||||
Rabbit F(ab')2 anti Mouse IgG:RPE | STAR12A | F | 1 ml |
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Description | Rabbit F(ab')2 anti Mouse IgG:RPE | ||||||
Rabbit F(ab')2 anti Mouse IgG:HRP (Human Adsorbed) | STAR13B | C E P RE WB | 1 mg |
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List Price | Your Price | ||||||
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Description | Rabbit F(ab')2 anti Mouse IgG:HRP (Human Adsorbed) | ||||||
Rabbit F(ab')2 anti Mouse IgG:FITC | STAR9B | F | 1 mg |
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List Price | Your Price | ||||||
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Description | Rabbit F(ab')2 anti Mouse IgG:FITC |
References for IgG antibody
-
Stubenrauch, K. et al. (2009) Evaluation of an immunoassay for human-specific quantitation of therapeutic antibodies in serum samples from non-human primates.
J Pharm Biomed Anal. 49 (4): 1003-8. -
Gilchuk, P. et al. (2018) Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in Nonhuman Primates.
J Infect Dis. 218 (suppl_5): S565-S573. -
Cross, R.W. et al. (2020) Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment.
Nat Commun. 11 (1): 3736. -
Gilchuk, P. et al. (2020) Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.
Immunity. 52 (2): 388-403.e12. -
Lovey, A. et al. (2024) CTC-177, a novel drug-Fc conjugate, shows promise as an immunoprophylactic agent against multidrug-resistant Gram-negative bacterial infections.
JAC Antimicrob Resist. 6 (4): dlae100.
- RRID
- AB_10965068
- UniProt
- P01857
- P01859
- P01859
- Entrez Gene
- IGHG1
- IGHG2
- GO Terms
- GO:0005515 protein binding
- GO:0003823 antigen binding
- GO:0005576 extracellular region
- GO:0005624 membrane fraction
- GO:0006955 immune response
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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