DNAJA1 antibody | AB01/4A12
Mouse anti DNAJA1 antibody recognizes DnaJ homolog subfamily A member 1, also known as DNAJ2, HDJ2, HSJ2, and HSPF4.
DNAJA1 is a member of the DNAJ family of proteins, the largest and most diverse family of co-chaperones that work with HCP70 and HSP90 (Ergülen et al. 2016). The DNAJ family has diverse involvement in cellular activities including protein translation, folding / unfolding / refolding, translocation and degradation (Parrales et al. 2016). DNAJA1 appears to play roles in autoimmune diseases, neurodegenerative diseases, and cancer (Ergülen et al. 2016). DNAJA1 also co-opted by and acts as a positive replicator for replication of the influenza A virus via its RNA polymerase activity (Cao et al. 2014).
DNAJA1 is a member of the DNAJ family of proteins, the largest and most diverse family of co-chaperones that work with HCP70 and HSP90 (Ergülen et al. 2016). The DNAJ family has diverse involvement in cellular activities including protein translation, folding / unfolding / refolding, translocation and degradation (Parrales et al. 2016). DNAJA1 appears to play roles in autoimmune diseases, neurodegenerative diseases, and cancer (Ergülen et al. 2016). DNAJA1 also co-opted by and acts as a positive replicator for replication of the influenza A virus via its RNA polymerase activity (Cao et al. 2014).
Product Details
- Target Species
- Human
- Western Blotting
- Mouse anti DNAJA1 antibody detects a band of approximately 46 kDa in HEK293 cell lysates
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - Liquid
- Preparation
- Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
- Immunogen
- E. coli-derived recombinant protein of amino acids 1-397 of human DNAJA1
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
Storage Information
- Storage
- Store undiluted at -20°C, avoiding repeated freeze thaw cycles
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P31689
- Entrez Gene
- DNAJA1
- GO Terms
- GO:0051082 unfolded protein binding
- GO:0006457 protein folding
- GO:0006986 response to unfolded protein
- GO:0016020 membrane
- GO:0046872 metal ion binding
- GO:0005524 ATP binding
- GO:0009408 response to heat
- GO:0031072 heat shock protein binding
- GO:0050750 low-density lipoprotein particle receptor binding
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only
Applications of DNAJA1 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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