CD71 (soluble) antibody | 13E4
KO Validated
IP-MS Validated
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WB IP ResetMouse anti CD71 (soluble)
- Product Type
- PrecisionAb Monoclonal
- Clone
- 13E4
- Isotype
- IgG2a
- Format
- Purified
- Specificity
- CD71 (soluble)
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| Mouse anti Human CD71 (soluble) antibody recognizes the human soluble transferrin receptor (sTfR) also known as sCD71 or p90. CD71 is a single pass type II membrane glycoprotein of ~90 kDa containing a single protease associated domain. sCD71 forms a homodimeric complex, a truncated form of the membrane bound transferrin receptor lacking the cytoplasmic and transmembrane regions of the molecule (Shih et al. 1990). It is responsible for the uptake of iron into the cell by binding to and internalizing iron-bound transferrin ( Mouse anti Human soluble CD71 recognizes human both the soluble transferrin receptor and the complex between soluble transferrin receptor and transferrin. The antibody recognizes CD71 as a single band of ~90 kDa in multiple human cell line lysates by western blotting under reducing conditions. |
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- Target Species
- Human
- Western Blotting
- Anti CD71 (soluble) antibody detects a band of approximately 90 kDa in K562 cell lysates.
- Product Form
- Purified IgG - liquid
- Preparation
- Mouse monoclonal antibody purified by affinity chromatography on Protein A from tissue culture supernatant.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3).
- Immunogen
- Purified human soluble transferrin receptor
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Regulatory
- For research purposes only.
- Guarantee
- 12 months from date of despatch.
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
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| Immunoprecipitation | |
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| Western Blotting | |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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| List Price | Your Price | ||||||
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| Description | Goat anti Mouse IgG (H/L):HRP | ||||||
- Synonyms
- Transferrin Receptor
- UniProt
- P02786
- Entrez Gene
- TFRC
- GO Terms
- GO:0008233 peptidase activity
- GO:0004998 transferrin receptor activity
- GO:0005887 integral to plasma membrane
- GO:0005768 endosome
- GO:0005905 coated pit
- GO:0006508 proteolysis
- GO:0006879 cellular iron ion homeostasis
- GO:0006897 endocytosis
- GO:0033572 transferrin transport
- View More GO Terms
- GO:0042470 melanosome
- GO:0044419 interspecies interaction between organisms
- GO:0055085 transmembrane transport
View more products with CD71 specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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