CD45 antibody | F10-89-4
Mouse anti Human CD45 antibody, clone F10-89-4 (MCA87) used for the evaluation of CD45 expression on brain derived mesenchymal stem cells.
Image caption:
FACS sorting of brain-derived progenitor cell lines. Human progenitor cells were positively sorted for the MSC markers CD105 and CD13, and thereafter negatively for hematopoietic (CD45) and endothelial markers (CD31). Histogram illustrates results (A, B) for the two different cortical lines and (C, D) for the two lines from the ventricular zone. 99.4–100% of the cell population expressed both, CD105 and CD13, and cultures did not contain endothelial or hematopoietic cells.
From: Paul G, Özen I, Christophersen NS, Reinbothe T, Bengzon J, et al. (2012) The Adult Human Brain Harbors Multipotent Perivascular Mesenchymal Stem Cells.
PLoS ONE 7(4): e35577.
This image is from an open access article distributed under the terms of the Creative Commons Attribution License.
Mouse anti Human CD45 antibody, clone F10-89-4 (MCA87GA) used for the evaluation of CD45 expression on brain derived mesenchymal stem cells.
Image caption:
Brain-derived cell lines express markers for mesenchymal stem cells and pericytes but not for glial or neuronal precursors. (A) Representative histogram of flow cytometry analysis of cortical line and (B) ventricular zone line. Progenitors from all donors and both regions highly express MSC (CD90, CD73, CD105, CD29, CD166 and CD49d) and pericyte markers (CD140b/PDGFR-β, RGS5, CD146, Nestin, α-SMA and NG2). They do not express hematopoietic (CD45), endothelial (CD31, CD34), microglial (CD14, CD11), glial or neuronal precursor cell markers (GFAP, O4) or myofibroblast markers (CD56), (green = isotype, red = respective marker).
From: Paul G, Özen I, Christophersen NS, Reinbothe T, Bengzon J, et al. (2012) The Adult Human Brain Harbors Multipotent Perivascular Mesenchymal Stem Cells.
PLoS ONE 7(4): e35577.
This image is from an open access article distributed under the terms of the Creative Commons Attribution License.
Mouse anti Human CD45 antibody, clone F10-89-4 (MCA87GA) used for the evaluation of CD45 expression on brain derived mesenchymal stem cells.
Image caption:
Characterisation of clonal perivascular MSC progenitor lines. (A) Single cell in vitro a few hours after plating, and culture at 7 and 21 days, respectively. Scale bar 50 µm. (B) Clonally derived MSC show the same antigen profile as detected for polyclonal lines with pericyte and MSC markers but neither neuronal nor glial precursor cell markers (O4, GFAP) (example here cortical clone; green = isotype, red = respective marker).(C) QPCR comparing clones derived from the ventricular zone (n = 2), and the cortex (n = 2) to a human neuronal progenitor cell line MesC2.10. Data show the relative higher expression of mRNA for RGS5, PDGFR-β and α-SMA in the MSC clones compared to the control. As expected, Nestin mRNA was present in perivascular MSC clones and neural progenitors at comparable amounts. NG2 mRNA was slightly higher expressed in the MSC clones compared to the control. (D) Importantly, neural progenitors markers such as CD133, SOX1, NGN2, PAX6 and Musashi were highly expressed in the positive control but not detectable in MSC clones.
From: Paul G, Özen I, Christophersen NS, Reinbothe T, Bengzon J, et al. (2012)
The Adult Human Brain Harbors Multipotent Perivascular Mesenchymal Stem Cells.
PLoS ONE 7(4): e35577.
This image is from an open access article distributed under the terms of the Creative Commons Attribution License.
Alexa Fluor A647 conjugated Mouse anti Human CD45 antibody, clone F10-89-4 (MCA87A647) used for the identification of CD45 expressing cells in blood samples by immunofluorescence.
Image caption:
Relocation and characterization of CTCs using the Wright-Giemsa stain. After initial identification of CTCs via fluorescent images, subsequent Wright-Giemsa stain and/or Papanicolau stain of these cells is performed: (a) composite 3-color fluorescent image, (b) DAPI channel only, (c) cytokeratin channel only, (d) CD45 channel only, and (e) corresponding Wright-Giemsa-stained cell.
From: Marrinucci D, Bethel K, Lazar D, Fisher J, Huynh E, Clark P, Bruce R, Nieva J, Kuhn P.
Cytomorphology of circulating colorectal tumor cells: a small case series.
J Oncol. 2010:861341.
This image is from an open access article distributed under the terms of the Creative Commons Attribution License.
Phycoerythrin conjugated Mouse anti Human CD45 antibody, clone F10-89-4 (MCA87PE) used to evaluate CD45 expression on bone-marrow derived mesenchymal stem cells by flow cytometry
Image caption:
From: Chaturvedi CP, Tripathy NK, Minocha E, Sharma A, Rahman K, Nityanand S.
Altered Expression of Hematopoiesis Regulatory Molecules in Lipopolysaccharide-Induced Bone Marrow Mesenchymal Stem Cells of Patients with Aplastic Anemia.
Stem Cells Int. 2018 Oct 17;2018:6901761.
This image is from an open access article distributed under the terms of the Creative Commons Attribution License.
AlexaFluor®647 conjugated Mouse anti Human CD45 antibody, clone F10-89-4 (MCA87A647) used to identify circulating white blood cells in blood samples containing circulating tumor cells by immunofluorescence.
Image caption:
HD-CTC and candidate CTC cell data for stage IV NSCLC. a Representative image of HD-CTC. HD-CTCs are cytokeratin positive (red), CD45 negative (green), contains a DAPI nucleus (blue) and is morphologically distinct from surrounding white blood cells. b–d Representative images of types of suspected candidate CTCs found in a single NSCLC patient. b Nucleus too small and cytoplasm insufficiently circumferential; cell appears to be in late apoptosis and defined as CTC-cfDNA producing. c Suspected CTC that is negative for cytokeratin and CD45, but has a nucleus that is morphologically similar to CTCs, defined as CTC-NoCytokeratin. d Nucleus is small (same size as surrounding WBC nuclei) and cytokeratin present, defined as CTC-Small. e Distribution of CTCs and candidate cells in NSCLC patients
From: Shishido SN, Carlsson A, Nieva J, Bethel K, Hicks JB, Bazhenova L, Kuhn P.
Circulating tumor cells as a response monitor in stage IV non-small cell lung cancer.
J Transl Med. 2019 Aug 28;17(1):294.
doi: 10.1186/s12967-019-2035-8.
This image is from an open access article distributed under the terms of the Creative Commons Attribution License.
Alexa Fluor A647 conjugated Mouse anti Human CD45 antibody, clone F10-89-4 (MCA87A647) used for the identification of CD45 expressing cells in human blood samples by immunofluorescence.
Image caption:
Representative CTCs found in Patients 1–5. Each column represents one patient's CTCs: Red = cytokeratin, Green = CD45, and Blue = DAPI.
From: Marrinucci D, Bethel K, Lazar D, Fisher J, Huynh E, Clark P, Bruce R, Nieva J, Kuhn P.
Cytomorphology of circulating colorectal tumor cells: a small case series.
J Oncol. 2010:861341.
This image is from an open access article distributed under the terms of a Creative Commons Attribution License.
Alexa Fluor 647 conjugated Mouse anti Human CD45 antibody, clone F10-89-4 (MCA87A647) used to identify leucocytes by immunofluorescence.
Image caption:
HDSCA3.0 Rare Event Gallery.
a. Images represent two candidate rare events, categorized by marker expression. b. Signal distribution of immunofluorescent markers for channel-classified cells. Designated colors represent each channel-classified group, assigned in a. (LEVs not included due to variation in segmentation). Scale bar represent 10 μm.
From: Setayesh SM, Hart O, Naghdloo A, Higa N, Nieva J, Lu J, Hwang S, Wilkinson K, Kidd M, Anderson A, Velasco CR, Kolatkar A, Matsumoto N, Nevarez R, Hicks JB, Mason J, Shishido SN, Kuhn P.
Multianalyte liquid biopsy to aid the diagnostic workup of breast cancer.
NPJ Breast Cancer. 2022 Sep 27;8(1):112.
doi: 10.1038/s41523-022-00480-4.
This image is from an open access article distributed under terms of a Creative Commons Attribution License.
Alexa Fluor® 647 conjugated Mouse anti Human CD45 antibody, clone F10-89-4 (MCA87A647) used to label rare cells in liquid biopsies by immunfluorescence.
Image caption:
Circulating rare cells identified in the peripheral blood from SCLC patient samples using HDSCA3.0 with the Landscape assay. (A) Representative cell images of each cell group. Each row shows a composite image plus each of the four channels separately; DAPI in blue, CK in red, Vim in white, (CD45/CD31) in green.
From: Seo J, Kumar M, Mason J, Blackhall F, Matsumoto N, Dive C, Hicks J, Kuhn P, Shishido SN.
Plasticity of circulating tumor cells in small cell lung cancer.
Sci Rep. 2023 Jul 21;13(1):11775.
doi: 10.1038/s41598-023-38881-5.
This image is from an open access article distributed under terms of a Creative Commons Attribution License.
Alexa Fluor® 647 conjugated Mouse anti Human CD45 antibody, clone F10-89-4 (MCA87A647) used to label rare cells in liquid biopsies by immunfluorescence.
Image caption:
Detected cells from UM-001 using the EpCAM assay. (A) Representative cell images of each cell group. Each row shows a composite image plus each of the four channels separately: DAPI in blue, CK in red, CD45 in green, and EpCAM in white. (B) The number of total rare cells per mL is provided. Each rare cell group is annotated with four different colors which are shown in the bottom right of the figure.
From: Seo J, Kumar M, Mason J, Blackhall F, Matsumoto N, Dive C, Hicks J, Kuhn P, Shishido SN.
Plasticity of circulating tumor cells in small cell lung cancer.
Sci Rep. 2023 Jul 21;13(1):11775.
doi: 10.1038/s41598-023-38881-5.
This image is from an open access article distributed under terms of a Creative Commons Attribution License.
Alexa Fluor 647 conjugated Mouse anti Human CD45 antibody, clone F10-89-4 (MCA87A647) used to label human leucocytes by immunofluorescence.
Image caption:
HDSCA3.0 gallery
a IF representative images of channel classification. Scale bar represents 10 μm.
From: Setayesh SM, Ndacayisaba LJ, Rappard KE, Hennes V, Rueda LYM, Tang G, Lin P, Orlowski RZ, Symer DE, Manasanch EE, Shishido SN, Kuhn P.
Targeted single-cell proteomic analysis identifies new liquid biopsy biomarkers associated with multiple myeloma.
NPJ Precis Oncol. 2023 Sep 18;7(1):95.
doi: 10.1038/s41698-023-00446-0.
This image is from an open access article distributed under terms of a Creative Commons Attribution License.
Alexa Fluor 647 conjugated Mouse anti Human CD45 antibody, clone F10-89-4 (MCA87A647) used to label cells in liquid biopsies from PDAC patients.
Image caption:
Representative gallery of rare events detected in samples collected from patients diagnosed with PDAC.
For each rare event the composite image is provided followed by the individual biomarker fluorescent channels which are indicated by the headers. a Epi.CTC; b Mes.CTC (top: single cell; middle: cluster of 2; bottom: cluster of 4); c DAPI|CK|Vim|CD45/CD31; d DAPI|CK|CD45/CD31; e DAPI|Vim|CD45/CD31 (top: single cell; bottom: cluster); f DAPI|Vim; g DAPI|CK|CD45/CD31; h DAPI-only; I CK oncosome; j CK|Vim oncosome; k CK|CD45/CD31 oncosomes; l CK|Vim|CD45/CD31 oncosome (top: distal, bottom: proximal). Blue: DAPI, Red: CK, White: Vim, Green: CD45/CD31. Images taken at 100X magnification. Scale bar = 10 μm.
From: Shishido SN, Lin E, Nissen N, Courcoubetis G, Suresh D, Mason J, Osipov A, Hendifar AE, Lewis M, Gaddam S, Pandol S, Kuhn P, Lo SK.
Cancer-related cells and oncosomes in the liquid biopsy of pancreatic cancer patients undergoing surgery.
NPJ Precis Oncol. 2024 Feb 15;8(1):36.
doi: 10.1038/s41698-024-00521-0.
This image is from an open access article distributed under terms of a Creative Commons Attribution License.
Alexa Fluor 647 conjugated Mouse anti Human CD45 monoclonal antibody, clone F10-89-4 (MCA87A647) used to detect CD45 positive events in liquid biopsy evaluation by immunofluorescence.
Image caption:
Representative images of rare events detected in the NSCLC patient blood samples. Images taken at 100x magnification. (a–h) Rare cells and (i–l) oncosomes. DAPI: blue, cytokeratin (CK): red, Vim: white, CD45/CD31: green (a): Epithelial like CTCs (Epi.CTCs), (b): CK|CD45/CD31 cell, (c): CK|Vim|CD45/CD31 cell, (d): Vim|CD45/CD31 cell, (e): Vim only cell, (f): CD45/CD31 cell, (g): DAPI only cell, (h): Mesenchymal like CTCs (Mes.CTCs), (i): Onc proximal to cell, (j): Onc alone
From: Bai L, Courcoubetis G, Mason J, Hicks JB, Nieva J, Kuhn P, Shishido SN.
Longitudinal tracking of circulating rare events in the liquid biopsy of stage III-IV non-small cell lung cancer patients.
Discov Oncol. 2024 May 3;15(1):142.
doi: 10.1007/s12672-024-00984-4.
This image is from an open access article distributed under terms of a Creative Commons Attribution License.
Alexa Fluor 488 conjugated Mouse anti Human CD45 antibody, clone F10-89-4 (MCA87A488) demonstrating negative staining on equine mesenchymal stem cells as analysed by flow cytometry.
Image caption:
MSC were harvested, stained with fluorescent-labeled monoclonal antibodies
The figure displays representative histograms of surface marker stainings (red) and the corresponding isotype controls (blue).
From: Moellerberndt J, Niebert S, Fey K, Hagen A, Burk J.
Impact of platelet lysate on immunoregulatory characteristics of equine mesenchymal stromal cells.
Front Vet Sci. 2024 Apr 24;11:1385395.
doi: 10.3389/fvets.2024.1385395.
This image is from an open access article distributed under terms of a Creative Commons Attribution License.
Mouse anti Human CD45:APC
- Product Type
- Monoclonal Antibody
- Clone
- F10-89-4
- Isotype
- IgG2a
- Specificity
- CD45
Antibody Quality and Performance Guarantee
| Mouse anti Human CD45 antibody, clone F10-89-4 recognizes the human CD45 cell surface antigen, also known as leucocyte common antigen (LCA). CD45 is a complex molecule existing in a number of isoforms. Antibodies recognizing a common epitope on all of these isoforms are termed CD45 whilst those recognizing only individual isoforms are termed CD45RA or CD45RO etc. Mouse anti Human CD45 antibody, clone F10-89-4 reacts with all forms of CD45 expressed by all haematopoietic cells, except erythrocytes, having a higher level of expression on lymphocytes than on granulocytes. It is routinely tested in flow cytometry on human peripheral blood leucocytes. Mouse anti Human CD45 antibody, clone F10-89-4, has been validated for use on the Genesis Cell Isolation System with the CelSelect SlideTM technology. |
|
- Target Species
- Human
- Product Form
- Purified IgG conjugated to Allophycocyanin (APC) - lyophilized
- Reconstitution
- MCA87APCT: Reconstitute in 0.25 ml disilled water
- MCA87APC: Reconstitute with 1 ml distilled water
- Preparation
- Purified IgG prepared by affinity chromatography from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide 1% Bovine Serum Albumin 5% Sucrose - Immunogen
- Human T lymphocytes.
- Fusion Partners
- Spleen cells from immunized BALB/c mice were fused with cells of the mouse NS-1 myeloma cell line.
- Max Ex/Em
-
Fluorophore Excitation Max (nm) Emission Max (nm) APC 650 661 - Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Prior to reconstitution store at +4oC. Following reconstitution store at +4oC.
DO NOT FREEZE.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
DO NOT FREEZE.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry |  |
Neat |
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood
How to Use the Spectraviewer
Watch the Tool Tutorial Video ▸- Start by selecting the application you are interested in, with the option to select an instrument from the drop down menu or create a customized instrument
- Select the fluorophores or fluorescent proteins you want to include in your panel to check compatibility
- Select the lasers and filters you wish to include
- Select combined or multi-laser view to visualize the spectra
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse IgG2a Negative Control:APC | MCA929APC | F | 100 Tests | Log in | |||
| List Price | Your Price | ||||||
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| Description | Mouse IgG2a Negative Control:APC | ||||||
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Human Seroblock | BUF070A | F | 50 Test | Log in | |||
| List Price | Your Price | ||||||
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| Description | Human Seroblock | ||||||
| Human Seroblock | BUF070B | F | 200 Test | Log in | |||
| List Price | Your Price | ||||||
| Log in | |||||||
| Description | Human Seroblock | ||||||
Source Reference
-
Dalchau, R. et al. (1980) Monoclonal antibody to a human leukocyte-specific membrane glycoprotein probably homologous to the leukocyte-common (L-C) antigen of the rat.
Eur J Immunol. 10 (10): 737-44.
References for CD45 antibody
-
Quenby, S et al. (1999) Pre-implantation endometrial leukocytes in women with recurrent miscarriage.
Human Reprod. 14(9):2386-2391. -
Hauser, P.V. et al. (2010) Stem cells derived from human amniotic fluid contribute to acute kidney injury recovery.
Am J Pathol. 177: 2011-21. -
Mallam, E. et al. (2010) Characterization of in vitro expanded bone marrow-derived mesenchymal stem cells from patients with multiple sclerosis.
Mult Scler. 16: 909-18. -
Marrinucci, D. et al. (2010) Cytomorphology of circulating colorectal tumor cells:a small case series.
J Oncol. 2010: 861341. -
Paul, G. et al. (2012) The adult human brain harbors multipotent perivascular mesenchymal stem cells.
PLoS One. 7: e35577. -
De Schauwer, C. et al. (2012) In search for cross-reactivity to immunophenotype equine mesenchymal stromal cells by multicolor flow cytometry.
Cytometry A. 81 (4): 312-23. -
Kazane, S.A. et al. (2012) Site-specific DNA-antibody conjugates for specific and sensitive immuno-PCR.
Proc Natl Acad Sci U S A. 109: 3731-6. -
Spaas, J.H. et al. (2013) Culture and characterisation of equine peripheral blood mesenchymal stromal cells.
Vet J. 195 (1): 107-13.
View The Latest Product References
-
Sadarangani, A. et al. (2015) GLI2 inhibition abrogates human leukemia stem cell dormancy.
J Transl Med. 13: 98. -
Gunawardene, P. et al. (2015) Association Between Circulating Osteogenic Progenitor Cells and Disability and Frailty in Older Persons: The Nepean Osteoporosis and Frailty Study.
J Gerontol A Biol Sci Med Sci. pii: glv190. -
Mohamed Suhaimi, N.A. et al. (2015) Non-invasive sensitive detection of KRAS and BRAF mutation in circulating tumor cells of colorectal cancer patients.
Mol Oncol. 9 (4): 850-60. -
Ruiz, C. et al. (2015) Limited genomic heterogeneity of circulating melanoma cells in advanced stage patients.
Phys Biol. 12 (1): 016008. -
Gogoi P et al. (2016) Development of an Automated and Sensitive Microfluidic Device for Capturing and Characterizing Circulating Tumor Cells (CTCs) from Clinical Blood Samples.
PLoS One. 11 (1): e0147400. -
Gomiero, C. et al. (2016) Tenogenic induction of equine mesenchymal stem cells by means of growth factors and low-level laser technology.
Vet Res Commun. 40 (1): 39-48. -
Bianchessi, M. et al. (2016) Effect of Fibroblast Growth Factor 2 on Equine Synovial Fluid Chondroprogenitor Expansion and Chondrogenesis.
Stem Cells Int. 2016: 9364974. -
Branly, T. et al. (2017) Characterization and use of Equine Bone Marrow Mesenchymal Stem Cells in Equine Cartilage Engineering. Study of their Hyaline Cartilage Forming Potential when Cultured under Hypoxia within a Biomaterial in the Presence of BMP-2 and TGF-β1.
Stem Cell Rev Rep. 13 (5): 611-30. -
GarikipatiV, N.S. et al. (2018) Isolation and characterization of mesenchymal stem cells from human fetus heart.
PLoS One. 13 (2): e0192244. -
Shishido, S.N. et al. (2019) Circulating tumor cells as a response monitor in stage IV non-small cell lung cancer.
J Transl Med. 17 (1): 294. -
Welter, L. et al. (2020) Treatment response and tumor evolution: lessons from an extended series of multianalyte liquid biopsies in a metastatic breast cancer patient.
Cold Spring Harb Mol Case Stud. 6 (6): a005819. -
Ndacayisaba, L.J. et al. (2022) Enrichment-Free Single-Cell Detection and Morphogenomic Profiling of Myeloma Patient Samples to Delineate Circulating Rare Plasma Cell Clones
Curr Oncol. 29 (5): 2954-72. -
Shishido, S.N. et al. (2022) Liquid Biopsy Landscape in Patients with Primary Upper Tract Urothelial Carcinoma.
Cancers (Basel). 14 (12): 3007. -
Chai, S. et al. (2022) Identification of epithelial and mesenchymal circulating tumor cells in clonal lineage of an aggressive prostate cancer case.
NPJ Precis Oncol. 6 (1): 41. -
Zhu, J. et al. (2022) Sequential Method for Analysis of CTCs and Exosomes from the Same Sample of Patient Blood.
ACS Omega. 7 (42): 37581-88. -
Setayesh, S.M. et al. (2022) Multianalyte liquid biopsy to aid the diagnostic workup of breast cancer.
NPJ Breast Cancer. 8 (1): 112. -
Ndacayisaba, L.J. et al. (2022) Characterization of BCMA Expression in Circulating Rare Single Cells of Patients with Plasma Cell Neoplasms.
Int J Mol Sci. 23 (21): 13427. -
Qi, E. et al. (2023) Investigation of liquid biopsy analytes in peripheral blood of individuals after SARS-CoV-2 infection.
EBioMedicine. 90: 104519. -
Seo, J. et al. (2023) Plasticity of circulating tumor cells in small cell lung cancer.
Sci Rep. 13 (1): 11775. -
Setayesh, S.M. et al. (2023) Targeted single-cell proteomic analysis identifies new liquid biopsy biomarkers associated with multiple myeloma.
NPJ Precis Oncol. 7 (1): 95. -
Welter, L. et al. (2023) Cell State and Cell Type: Deconvoluting Circulating Tumor Cell Populations in Liquid Biopsies by Multi-Omics.
Cancers (Basel). 15 (15): 3949. -
Shishido, S.N. et al. (2024) Cancer-related cells and oncosomes in the liquid biopsy of pancreatic cancer patients undergoing surgery.
NPJ Precis Oncol. 8 (1): 36. -
Bai, L. et al. (2024) Longitudinal tracking of circulating rare events in the liquid biopsy of stage III-IV non-small cell lung cancer patients.
Discov Oncol. 15 (1): 142. -
Shishido, S.N. et al. (2024) Determining the efficacy of ExThera Seraph100 blood filtration in patients diagnosed with pancreatic cancer through the liquid biopsy
BJC Reports. 2: 47. -
Moellerberndt, J. et al. (2024) Impact of platelet lysate on immunoregulatory characteristics of equine mesenchymal stromal cells.
Front Vet Sci. 11: 1385395.
- Synonyms
- LCA
- RRID
- AB_324884
- UniProt
- P08575
- Entrez Gene
- PTPRC
- GO Terms
- GO:0001915 negative regulation of T cell mediated cytotoxicity
- GO:0001960 negative regulation of cytokine-mediated signaling pathway
- GO:0002378 immunoglobulin biosynthetic process
- GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
- GO:0005887 integral to plasma membrane
- GO:0005925 focal adhesion
- GO:0006469 negative regulation of protein kinase activity
- GO:0006470 protein dephosphorylation
- GO:0007411 axon guidance
- View More GO Terms
- GO:0019901 protein kinase binding
- GO:0030890 positive regulation of B cell proliferation
- GO:0033261 regulation of S phase
- GO:0042100 B cell proliferation
- GO:0045121 membrane raft
- GO:0050852 T cell receptor signaling pathway
- GO:0050853 B cell receptor signaling pathway
- GO:0050857 positive regulation of antigen receptor-mediated signaling pathway
- GO:0051209 release of sequestered calcium ion into cytosol
- GO:0051607 defense response to virus
MCA87APCT
INN1702
MCA87APC
INN1702
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