Rat anti Human c-myc antibody, clone JAC6 recognises the myc proto-oncogene which is frequently used to tag proteins, and is the same epitope recognised by clone 9E10. c-myc is also known as Transcription factor p64 orClass E basic helix-loop-helix protein 39.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Carrier Free
- Amino acids 408-439 corresponding to the C-terminal region of human c-myc.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
branching involved in ureteric bud morphogenesis
sequence-specific DNA binding transcription factor activity
regulation of transcription from RNA polymerase II promoter
cellular iron ion homeostasis
cell cycle arrest
response to drug
transcription activator activity
regulation of telomere maintenance
positive regulation of metanephric cap mesenchymal cell proliferation
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of c-Myc antibody
|Immunohistology - Frozen
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available
Application Based External Images
Product Specific References
References for c-Myc antibody
Smith, G.D. et al. (2002) TRPV3 is a temperature-sensitive vanilloid receptor-like protein.
Nature. 418 (6894): 186-90.
Dawson, K. et al. (2008) Loss of regulators of vacuolar ATPase function and ceramide synthesis results in multidrug sensitivity in Schizosaccharomyces pombe.
Eukaryot Cell. 7 (6): 926-37.
Tetzlaff, J.E. et al. (2008) CHIP targets toxic alpha-Synuclein oligomers for degradation.
J Biol Chem. 283 (26): 17962-8.
Shin, Y. et al. (2005) The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alpha-synuclein degradation decisions between proteasomal and lysosomal pathways.
J Biol Chem. 280 (25): 23727-34.
Liebig, T. et al. (2009) RhoE Is required for keratinocyte differentiation and stratification.
Mol Biol Cell. 20 (1): 452-63.
Lozano, E. et al. (2008) PAK is required for the disruption of E-cadherin adhesion by the small GTPase Rac.
J Cell Sci. 121 (Pt 7): 933-8.
Stahl, R. et al. (2014) Shedding of APP limits its synaptogenic activity and cell adhesion properties.
Front Cell Neurosci. 8: 410.
Smith, M.D. et al. (2018) CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis.
Dev Cell. 44 (2): 217-232.e11.
Jenkins, P.M. et al. (2009) PACS-1 mediates phosphorylation-dependent ciliary trafficking of the cyclic-nucleotide-gated channel in olfactory sensory neurons.
J Neurosci. 29 (34): 10541-51.
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