ACTR2 antibody | CD01/1A6
siRNA Validated
Mouse anti ACTR2
- Product Type
- PrecisionAb Monoclonal
- Clone
- CD01/1A6
- Isotype
- IgG2b
- Format
- Purified
- Specificity
- ACTR2
Antibody Quality and Performance Guarantee
| Mouse anti ACTR2 antibody recognizes actin-related protein 2, also known as ARP2. Arp2 and Arp3 are part of the Arp2/3 complex, a multiprotein complex capable of generating branched actin networks. Actin cytoskeleton branching is essential for efficient cell migration, and silencing almost any subunit of the Arp2/3 complex has been shown to lead to a significant decrease in cell migratory capability (Rauhala et al. 2013). When activated, Arp2 and Arp3 are brought together within the complex. The active complex cross-links polymerizing actin filaments and exerts a pushing force (Molinie and Gautreau 2018). Phosphorylation of Arp2 by NIK is required for the activity of the Arp2/3 complex (LeClaire et al. 2015). |
|
- Target Species
- Human
- Western Blotting
- Mouse anti ACTR2 antibody detects a band of approximately 40 kDa in HeLa cell lysates
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - Liquid
- Preparation
- Mouse monoclonal antibody affinity purified on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
- Immunogen
- E. coli-derived recombinant protein of amino acids 1-394 of human ACTR2
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Fusion Partners
- Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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| List Price | Your Price | ||||||
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| Description | Goat anti Mouse IgG (H/L):HRP | ||||||
- UniProt
- P61160
- Entrez Gene
- ACTR2
- GO Terms
- GO:0003779 actin binding
- GO:0005524 ATP binding
- GO:0005737 cytoplasm
- GO:0005885 Arp2/3 protein complex
- GO:0006928 cellular component movement
- GO:0042995 cell projection
VMA00894
100004237
64580662
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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