SLPI antibody
Rabbit anti SLPI
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- SLPI
Rabbit anti Human SLPI antibody recognizes secretory leukocyte protease inhibitor (SLPI), a ~14 kDa non-glycosylated protein produced by secretory cells in the respiratory, genital and lachrymal glands, and by macrophages, B-cells and neutrophils. The functions of SLPI are diverse. The SLPI protein inhibits protease activity at sites of inflammation, protecting tissues against protease mediated damage and it possesses anti-microbial/anti-viral activity. In addition, SLPI has been reported to exhibit anti-inflammatory properties, regulating lipopolysaccharide induced activation of NF-kappa beta in peripheral blood monocytes. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to human SLPI were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.02% Sodium Azide - Immunogen
- A 17 amino acid peptide located near the centre of human SLPI.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunohistology - Paraffin 1 | |||
Western Blotting | 1.0 | 2.0ug/ml |
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
- Western Blotting
- AHP1437 detects a band of approximately 14kDa in Daudi cell lysates.
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Antigen Retrieval Buffer, pH8.0 | BUF025A | P | 500 ml | Log in | |||
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Description | Antigen Retrieval Buffer, pH8.0 | ||||||
TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB * | 0.5 ml | Log in | |||
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Description | TidyBlot Western Blot Detection Reagent:HRP |
- Synonyms
- HUSI-1
- RRID
- AB_2195061
- UniProt
- P03973
- Entrez Gene
- SLPI
- GO Terms
- GO:0005576 extracellular region
- GO:0004867 serine-type endopeptidase inhibitor activity
AHP1437
147071 157979If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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