IL-13 antibody
Rabbit anti Human Interleukin-13
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- IL-13
Rabbit Anti-Human Interleukin-13 Antibody is a polyclonal antibody that recognizes human interleukin 13 (IL-13), a secreted cytokine also known as NC30. IL-13 is a member of the type 2 cytokine family. This antibody has been reported to work in the following applications: ELISA, Western Blotting and functional assays. IL-13 is an immunoregulatory cytokine that plays a central role in type 2 immune responses, including allergic inflammation and host defense against parasitic infection. It is produced predominantly by activated T helper 2 (Th2) cells and by other immune cell types such as mast cells, basophils, and eosinophils, and it is secreted into the extracellular space. It acts on cells expressing IL 13 receptor complexes, including IL-13 receptor alpha 1 (IL13RA1) in combination with IL-4 receptor alpha (IL4RA), as well as the high affinity decoy receptor IL13RA2. |
- Target Species
- Human
- Product Form
- Purified IgG - lyophilized
- Reconstitution
- Reconstitute with 0.1 ml distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently vortexed after reconstitution and microcentrifuged before use.
- Antiserum Preparation
- Antisera to human IL-13 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by antigen affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present.
- Carrier Free
- Yes
- Immunogen
- Recombinant human IL-13.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Prior to reconstitution store at -20°C.
After reconstitution store at -20°C.
This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA | 0.5ug/ml (direct ELISA) | ||
| Functional Assays | 0.12ug/ml | 0.15ug/ml | |
| Western Blotting | 0.1ug/ml | 0.2ug/ml |
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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| Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
| Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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| Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
| Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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| Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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| Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
| Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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| Description | Sheep anti Rabbit IgG:RPE | ||||||
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB * | 0.5 ml | Log in | |||
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| Description | TidyBlot Western Blot Detection Reagent:HRP | ||||||
References for IL-13 antibody
-
Zheng, X. et al. (2010) TSLP and downstream molecules in experimental mouse allergic conjunctivitis.
Invest Ophthalmol Vis Sci. 51: 3076-82
- RRID
- AB_323635
- UniProt
- P35225
- Entrez Gene
- IL13
- GO Terms
- GO:0007165 signal transduction
- GO:0005125 cytokine activity
- GO:0005615 extracellular space
- GO:0005625 soluble fraction
- GO:0006928 cellular component movement
- GO:0006954 inflammatory response
- GO:0006955 immune response
- GO:0007267 cell-cell signaling
AHP291G
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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