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CX3CR1 antibody

Product Code Applications Pack Size List Price Your Price Qty
AHP566
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
F WB 0.1 mg loader
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loader

Rabbit anti human CX3CR1 polyclonal antibody recognizes CX3CR1, a seven transmembrane protein recently identified as a receptor for fractalkine. CX3CR1 is expressed in a variety of human tissues and mediates leucocyte adhesion and migration.

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antisera to CX3CR1 were raised by repeated immunisation of rabbit with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02%Sodium Azide
Immunogen
Peptide corresponding to amino acids 175 to 189 of human CX3CR1.
Approx. Protein Concentrations
IgG concentration 1 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry
Western Blotting 1/500
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.

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References for CX3CR1 antibody

  1. Corcione, A. et al. (2009) CX3CR1 is expressed by human B lymphocytes and meditates CX3CL1 driven chemotaxis of tonsil centrocytes.
    PLoS One. 4: e8485.
  2. Yildirim, C. et al. (2023) Parkinson’s disease-derived α-Synuclein assemblies combined with chronic-type inflammatory cues promote a neurotoxic microglial phenotype.
    bioRχiv. Dec 9 [Epub ahead of print].

Further Reading

  1. Imai, T. et al. (1997) Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion.
    Cell. 91: 521-30.

Flow Cytometry

Synonyms
Fractalkine Receptor
RRID
AB_2087422
UniProt
P49238
Entrez Gene
CX3CR1
GO Terms
GO:0007155 cell adhesion
GO:0004950 chemokine receptor activity
GO:0005887 integral to plasma membrane
GO:0006968 cellular defense response
GO:0009611 response to wounding
GO:0044419 interspecies interaction between organisms

AHP566

144518 147464

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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