The Bcl-2 Family members share varying numbers of Bcl-2 homology (BH) domains. The Bcl-2 family is heavily involved in the regulation of apoptosis. Their interactions control the permeability of the mitochondrial membrane. Loss of mitochondrial membrane integrity is a crucial step in apoptosis. The Bcl-2 family consists of members that are capable of promoting or inhibiting apoptosis.
Our full range of Bcl-2 Family antibodies, as highlighted above, come in a variety of formats and can be used for applications including western blotting, immunofluorescence, immunohistochemistry, immunoprecipitation and ELISA.
Please use the filters / buttons to select the antibody that fits your exact requirements. If you need any further assistance please do not hesitate to contact us.