- Target Species
- Product Form
- Purified monoclonal IgM - liquid
- Purified IgM prepared by affinity chromatography from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Single band by agarose electrophoresis and immunoelectrophoresis.
- Approx. Protein Concentrations
- IgM concentration 1.0 mg/ml
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- Entrez Gene
- GO Terms
activation of MAPK activity
humoral immune response mediated by circulating immunoglobulin
transmembrane receptor activity
external side of plasma membrane
B cell receptor complex
antigen processing and presentation
positive regulation of B cell proliferation
immunoglobulin complex, circulating
positive regulation of MAPKKK cascade
early endosome to late endosome transport
positive regulation of endocytosis
perinuclear region of cytoplasm
positive regulation of peptidyl-tyrosine phosphorylation
B cell receptor signaling pathway
integral to membrane
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Where this protein has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the protein for use in their own system using appropriate negative/positive controls.
Copyright © 2020 Bio-Rad Antibodies (formerly AbD Serotec)
Product Specific References
References for IgM
Hayer, S. et al. (2008) B-cell infiltrates induce endosteal bone formation in inflammatory arthritis.
J Bone Miner Res. 23: 1650-60.
Rohrer, J.W. et al. (2006) Identification of oncofetal antigen/immature laminin receptor protein epitopes that activate BALB/c mouse OFA/iLRP-specific effector and regulatory T cell clones.
J Immunol. 176: 2844-56.