Goat anti Rotavirus antibody reacts with rotavirus and is specific for ICPs and late structural (virion) antigens. It has been reported to exhibit 90% cross reactivity with human rotavirus and does not react with HEp-2 cells or WI-38 cells in immunofluorescence.
Rotavirus is a virus that infects the bowels and is the most common cause of gastroenteritis in infants. 7 major groups have currently been identified, 3 of which infect humans (groups A, B and C). The rotavirus genome consists of 11 segments of double stranded RNA held in the inner core of the three layered, icosahedral virion particle. The genome codes for 6 virus proteins (VP1,2,3,4,6,7) and 6 non-structural proteins (NSP1-6). Outer capsid proteins are VP4 and VP7, inner capsid -VP6 and core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection; therefore, multiple serotypes of rotavirus mean multiple opportunities for infection.
- Target Species
- Product Form
- Ig fraction - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Nebraska calf diarrhea virus.
- Approx. Protein Concentrations
- 4.0 mg/ml
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
- 12 months from date of despatch
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Rotavirus antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
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Secondary Antibodies Available
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