Human Immunodeficiency Virus 1 gp41 antibody
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Goat anti Human Immunodeficiency Virus 1 gp41
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- Human Immunodeficiency Virus 1 gp41
Antibody Quality and 
Unrivaled 
| Goat anti Human Immunodeficiency Virus 1 gp41 antibody reacts strongly with Immunodeficiency Virus 1 gp41, gp120 and gp160 in western blot assays. ELISA based peptide mapping has confirmed high titer reactivity to HIV MN env peptide in the following regions: (6332)IEPLGVAPTKAKRRV, (6360)CTTTVPWNASWSNKS and moderate activity to multiple other regions on the env polypeptide. The viral envelope protein gp160 is cleaved into fragments gp120 and gp41. gp120 is an exterior envelope glycoprotein on the surface of the virus particle that binds to CD4 and chemokine receptors on macrophages and T-lymphocytes. gp41 is non-covalently bound to gp120 and aids the virus in entering the cell. |
- Target Species
- Viral
- Product Form
- Purified IgG - liquid
- Buffer Solution
- 150mM Sodium chloride
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Immunogen
- Recombinant HIV1 gp41 antigen.
- Purity
- >98%
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
||
| Western Blotting | |
1/2,000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
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References for Human Immunodeficiency Virus 1 gp41 antibody
-
Stefansson S et al. (2013) High-throughput Peptide epitope mapping using carbon nanotube field-effect transistors.
Int J Pept. 2013: 849303.
- Synonyms
- HIV-1
- RRID
- AB_10851213
- UniProt
- Q70626
- GO Terms
- GO:0006915 apoptosis
- GO:0016021 integral to membrane
- GO:0005198 structural molecule activity
- GO:0019031 viral envelope
- GO:0019059 initiation of viral infection
- GO:0020002 host cell plasma membrane
- GO:0030260 entry into host cell
- GO:0030683 evasion by virus of host immune response
- GO:0044175 host cell endosome membrane
- View More GO Terms
- GO:0055036 virion membrane
View more products with HUMAN IMMUNODEFICIENCY VIRUS specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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