Herpes simplex Virus 1/2 antibody

Goat anti Herpes simplex Virus 1/2

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Herpes simplex Virus 1/2

Product Code Applications Pack Size List Price Your Price Qty
4956-0104
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SDS Safety Datasheet SDS
IF 1 ml loader
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Goat anti Herpes simplex Virus 1/2 antibody reacts with Herpes Simplex virus 1 and 2, recognizing infected cell proteins (ICPs) and late structural (virion) antigens. Goat anti Herpes simplex Virus 1/2 antibody does not react with HEp-2 cells.

Herpes Simplex virus (HSV) is a double stranded DNA virus of which there are 2 types, HSV1 and HSV2. HSV1 usually establishes latency in the trigeminal ganglion, a collection of nerve cells near the ear. From the trigeminal ganglion, it tends to recur on the lower lip or face causing cold sores. HSV2 usually resides in the sacral ganglion at the base of the spine. From there, it recurs in the genital area.

Target Species
Viral
Product Form
Purified IgG - liquid
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.1%Sodium Azide (NaN3)
Immunogen
Human HSV type 1, Strain F
Approx. Protein Concentrations
IgG concentration 4.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunofluorescence
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

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References for Herpes simplex Virus 1/2 antibody

  1. Sufiawati, I. and Tugizov, S.M. (2014) HIV-associated disruption of tight and adherens junctions of oral epithelial cells facilitates HSV-1 infection and spread.
    PLoS One. 9: e88803.
  2. Civitelli, L. et al. (2015) Herpes simplex virus type 1 infection in neurons leads to production and nuclear localization of APP intracellular domain (AICD): implications for Alzheimer's disease pathogenesis.
    J Neurovirol. 21 (5): 480-90.
  3. Marcocci, M.E. et al. (2018) The Amphibian Antimicrobial Peptide Temporin B Inhibits In Vitro Herpes Simplex Virus 1 Infection.
    Antimicrob Agents Chemother. 62 (5)Apr 26 [Epub ahead of print].
  4. Di Sotto, A. et al. (2018) A Polyphenol Rich Extract from Solanum melongena L. DR2 Peel Exhibits Antioxidant Properties and Anti-Herpes Simplex Virus Type 1 Activity In Vitro.
    Molecules. 23 (8)Aug 17 [Epub ahead of print].

RRID
AB_618826
View more products with HERPES specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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