Rabbit anti Ovine interleukin-6 antibody recognizes ovine interleukin-6 (IL-6). No cross-reactivity is seen with ovine IL-1 beta, IL-8, MCP or TNF alpha.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Serum - liquid (diluted)
- Antiserum Preparation
- Antisera to ovine IL-6 were raised by repeated immunisation of rabbits with highly purified antigen.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Recombinant IL-6.
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
interleukin-6 receptor binding
growth factor activity
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of IL-6 antibody
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
- The antibody may be used in a sandwich ELISA as a detection reagent for ovine IL-6, in combination with MCA1659 as a capture antibody.
Copyright © 2021 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
Useful Reagents Available
Product Specific References
References for IL-6 antibody
Stephens, S. et al. (2003) Differences in cytokine synthesis by the subpopulations of dendritic cells from afferent lymph.
Immunology. 120: 48-57.
Herath, S. et al. (2009) Expression of genes associated with immunity in the endometrium of cattle with disparate postpartum uterine disease and fertility.
Reprod Biol Endocrinol. 7: 55.
Wang, Z. et al. (2008) Acute hypercapnia improves indices of tissue oxygenation more than dobutamine in septic shock.
Am J Respir Crit Care Med. 177: 178-83.
Su, F. et al (2007) Beneficial effects of ethyl pyruvate in septic shock from peritonitis.
Arch Surg.142: 166-71.
Karisnan, K. et al. (2015) Interleukin-1 Receptor Antagonist Protects against Lipopolysaccharide Induced Diaphragm Weakness in Preterm Lambs.
PLoS One. 10 (4): e0124390.
Xu, A. et al. (2015) The Ovine Fetal and Placental Inflammatory Response to Umbilical Cord Occlusions With Worsening Acidosis.
Reprod Sci. 22 (11): 1409-20.
Dooley, L.M. et al. (2015) Effect of mesenchymal precursor cells on the systemic inflammatory response and endothelial dysfunction in an ovine model of collagen-induced arthritis.
PLoS One. 10 (5): e0124144.
Herry, C.L. et al. (2016) Temporal Patterns in Sheep Fetal Heart Rate Variability Correlate to Systemic Cytokine Inflammatory Response: A Methodological Exploration of Monitoring Potential Using Complex Signals Bioinformatics.
PLoS One. 11 (4): e0153515.
Westover, A. et al. (2017) Effect of Human Amnion Epithelial Cells on the Acute Inflammatory Response in Fetal Sheep.
Front Physiol. 8: 871.
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