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IL-6 antibody

Rabbit anti Sheep Interleukin-6

Product Type
Polyclonal Antibody
Polyclonal IgG

Product Code Applications Pack Size List Price Your Price Qty
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E WB 0.1 ml loader
List Price Your Price

Rabbit anti Ovine interleukin-6 antibody recognizes ovine interleukin-6 (IL-6). No cross-reactivity is seen with ovine IL-1 beta, IL-8, MCP or TNF alpha.

Target Species
Species Cross-Reactivity
Target SpeciesCross Reactivity
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Serum - liquid (diluted)
Antiserum Preparation
Antisera to ovine IL-6 were raised by repeated immunisation of rabbits with highly purified antigen.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
<0.1% Sodium Azide (NaN3)
Recombinant IL-6.
For research purposes only
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/500
Western Blotting
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
The antibody may be used in a sandwich ELISA as a detection reagent for ovine IL-6, in combination with MCA1659 as a capture antibody.

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References for IL-6 antibody

  1. Stephens, S. et al. (2003) Differences in cytokine synthesis by the subpopulations of dendritic cells from afferent lymph.
    Immunology. 120: 48-57.
  2. Herath, S. et al. (2009) Expression of genes associated with immunity in the endometrium of cattle with disparate postpartum uterine disease and fertility.
    Reprod Biol Endocrinol. 7: 55.
  3. Wang, Z. et al. (2008) Acute hypercapnia improves indices of tissue oxygenation more than dobutamine in septic shock.
    Am J Respir Crit Care Med. 177: 178-83.
  4. Su, F. et al (2007) Beneficial effects of ethyl pyruvate in septic shock from peritonitis.
    Arch Surg.142: 166-71.
  5. Karisnan, K. et al. (2015) Interleukin-1 Receptor Antagonist Protects against Lipopolysaccharide Induced Diaphragm Weakness in Preterm Lambs.
    PLoS One. 10 (4): e0124390.
  6. Xu, A. et al. (2015) The Ovine Fetal and Placental Inflammatory Response to Umbilical Cord Occlusions With Worsening Acidosis.
    Reprod Sci. 22 (11): 1409-20.
  7. Dooley, L.M. et al. (2015) Effect of mesenchymal precursor cells on the systemic inflammatory response and endothelial dysfunction in an ovine model of collagen-induced arthritis.
    PLoS One. 10 (5): e0124144.
  8. Herry, C.L. et al. (2016) Temporal Patterns in Sheep Fetal Heart Rate Variability Correlate to Systemic Cytokine Inflammatory Response: A Methodological Exploration of Monitoring Potential Using Complex Signals Bioinformatics.
    PLoS One. 11 (4): e0153515.
  9. View The Latest Product References
  10. Westover, A. et al. (2017) Effect of Human Amnion Epithelial Cells on the Acute Inflammatory Response in Fetal Sheep.
    Front Physiol. 8: 871.
  11. Castel, A. et al. (2021) Recording and manipulation of vagus nerve electrical activity in chronically instrumented unanesthetized near term fetal sheep.
    J Neurosci Methods. 360: 109257.
  12. Damiano, S. et al. (2022) Red orange and lemon extract preserve from oxidative stress, DNA damage and inflammatory status in lambs
    It J Anim Sci. 21 (1): 934-42.
  13. Cao, M. et al. (2024) The Vagus Nerve Regulates Immunometabolic Homeostasis in the Ovine Fetus near Term: The Impact on Terminal Ileum.
    Biology (Basel).13 (1): 38.
  14. Ciliberti, M.G. et al. (2024) Role of hazelnut skin supplementation on plasma antioxidant status and cytokine profile in growing lambs.
    Front Vet Sci. 11: 1340141.

Entrez Gene
GO Terms
GO:0006953 acute-phase response
GO:0005125 cytokine activity
GO:0005138 interleukin-6 receptor binding
GO:0005615 extracellular space
GO:0006955 immune response
GO:0008083 growth factor activity


130815 151200

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