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IgE antibody

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Anti Mouse IgE Antibody thumbnail image 1 Anti Mouse IgE Antibody thumbnail image 2
Anti Mouse IgE Antibody gallery image 1
Published customer image:
Goat anti Mouse IgE antibody (STAR110) used as a coating reagent in a sandwich ELISA to assess IgE levels in murine serum samples.
Image caption:
a–c Levels of total IgE (a), HDM-specific IgE (b), and HDM-specific IgG (c) 24 h after theanti Mouse last HDM challenge. Results show values from individual mice with bars indicating mean ± SEM from n = 12 mice (PBS/PBS group), n = 16 mice (CRM197/PBS group), n = 19 mice (IL-13-K/HDM group), or n = 20 mice (IL-4-K and IL-4-K + IL-13-K groups) pooled from two independent experiments.

From: Conde E, Bertrand R, Balbino B, Bonnefoy J, Stackowicz J, Caillot N, Colaone F, Hamdi S, Houmadi R, Loste A, Kamphuis JBJ, Huetz F, Guilleminault L, Gaudenzio N, Mougel A, Hardy D, Snouwaert JN, Koller BH, Serra V, Bruhns P, Grouard-Vogel G, Reber LL.
Dual vaccination against IL-4 and IL-13 protects against chronic allergic asthma in mice.
Nat Commun. 2021 May 11;12(1):2574.
doi: 10.1038/s41467-021-22834-5.
This image is from an open access article distributed under terms of a Creative Commons Attribution License.
Anti Mouse IgE Antibody gallery image 2
Published customer image:
Horseradish peroxidase conjugated Goat anti Mouse IgE antibody (STAR110P) used as a detection reagent in a sandwich ELISA to evaluate IgE expression in murine serum samples.
Image caption:
Peribronchila inflammation score and immunoglobulin levels in serum. The peribronchial inflammation score and OVA-sIgE levels in OVA group and OVA323-339 group were significantly increased, but they were significantly decreased accompanied by increased OVA-sIgG1 after OVA323-339MAP treatment (* compared with the control group, P <0.05; # compared with the OVA323-339 group, P <0.05). Data represent one of three independent experiments.

From: Su W, Zhong W, Zhang Y, Xia Z.
Synthesized OVA323-339MAP octamers mitigate OVA-induced airway inflammation by regulating Foxp3 T regulatory cells.
BMC Immunol. 2012 Jul 6;13:34.
doi: 10.1186/1471-2172-13-34.
This image is from an open access article distributed under terms of a Creative Commons Attribution License.

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E

Goat anti Mouse IgE

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
IgE

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Product Code Applications Pack Size List Price Your Price Qty
STAR110
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E 0.5 mg loader
List Price Your Price
loader

Goat anti mouse IgE polyclonal antibody recognizes mouse IgE and shows negligible cross - reactivity with other immunoglobulins.

Target Species
Mouse
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography
Antiserum Preparation
Antisera to mouse IgE were raised by repeated immunisations of goats with highly purified antigen.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
<0.1% Sodium Azide (NaN3)
Immunogen
Native mouse IgE.
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/100 1/1000
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.

Description Product Code Applications Pack Size List Price Your Price Quantity
Rabbit anti Goat IgG (Fc):FITC STAR122F F 1 mg loader
List Price Your Price
loader
Description Rabbit anti Goat IgG (Fc):FITC
Rabbit anti Goat IgG (Fc):HRP STAR122P C E WB 1 mg loader
List Price Your Price
loader
Description Rabbit anti Goat IgG (Fc):HRP

References for IgE antibody

  1. Xia,Z.W. et al (2007) Heme oxygenase-1 attenuates ovalbumin-induced airway inflammation by up-regulation of foxp3 T-regulatory cells, interleukin-10, and membrane-bound transforming growth factor- 1.
    Am J Pathol. 171: 1904-14.
  2. Hartmann, W. et al. (2011) A novel and divergent role of granzyme a and B in resistance to helminth infection.
    J Immunol. 186: 2472-81.
  3. Hadzhieva, M. et al. (2015) Mechanism and functional implications of the heme-induced binding promiscuity of IgE.
    Biochemistry. 54 (11): 2061-72.
  4. Su, W. et al. (2012) Synthesized OVA323-339MAP octamers mitigate OVA-induced airway inflammation by regulating Foxp3 T regulatory cells.
    BMC Immunol. 13: 34.
  5. Conde, E. et al. (2021) Dual vaccination against IL-4 and IL-13 protects against chronic allergic asthma in mice.
    Nat Commun. 12 (1): 2574.
  6. Mai, H.L. et al. (2020) Targeting the interleukin-7 receptor alpha by an anti-CD127 monoclonal antibody improves allergic airway inflammation in mice.
    Clin Exp Allergy. 50 (7): 824-834.

ELISA

RRID
AB_324344
UniProt
P06336
Entrez Gene
Gm900
GO Terms
GO:0003823 antigen binding

STAR110

151187 154157 160518

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