Rabbit anti CYR61 antibody recognizes cysteine-rich angiogenic inducer 61 (CYR61) also known as insulin-like growth factor-binding protein 10 (IGFBP-10/ IBP-10). CYR61 interacts with integrin receptors thereby regulating a variety of processes including cell proliferation and cell adhesion. CYR61 has also been shown to play a role in angiogenesis, inflammation and chemotaxis.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
||Expected from Sequence
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 30% Glycerol
0.5% Bovine Serum Albumin
- Synthetic peptide surrounding amino acid 166 of mouse CYR61
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
regulation of cell growth
atrioventricular valve morphogenesis
apoptosis involved in heart morphogenesis
ventricular septum development
insulin-like growth factor binding
oxygen and reactive oxygen species metabolic process
positive regulation of phospholipase activity
positive regulation of cell-substrate adhesion
extracellular matrix binding
extracellular matrix organization
positive regulation of cell migration
positive regulation of apoptosis
negative regulation of apoptosis
positive regulation of caspase activity
positive regulation of cell differentiation
response to protein stimulus
atrial septum morphogenesis
labyrinthine layer blood vessel development
positive regulation of cartilage development
positive regulation of ceramide biosynthetic process
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of CYR61 antibody
|Immunohistology - Paraffin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti CYR61 antibody recognizes a band of approximately 42 kDa in Jurkat cell lysate and mouse small intestine tissue lysates
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Secondary Antibodies Available
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