CYR61 antibody

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Rabbit anti CYR61

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
AHP2301 P WB 50 µg
Rabbit anti CYR61 antibody recognizes cysteine-rich angiogenic inducer 61 (CYR61) also known as insulin-like growth factor-binding protein 10 (IGFBP-10/ IBP-10). CYR61 interacts with integrin receptors thereby regulating a variety of processes including cell proliferation and cell adhesion. CYR61 has also been shown to play a role in angiogenesis, inflammation and chemotaxis.

Product Details

Target Species
Mouse
Species Cross-Reactivity
Target SpeciesCross Reactivity
Human
Rat Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
30% Glycerol
0.5% Bovine Serum Albumin
0.01% Thiomersal
Immunogen
Synthetic peptide surrounding amino acid 166 of mouse CYR61
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml

Storage Information

Storage
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
12 months from date of despatch

More Information

UniProt
P18406 Related reagents
Entrez Gene
Cyr61 Related reagents
GO Terms
GO:0001558 regulation of cell growth
GO:0001649 osteoblast differentiation
GO:0002041 intussusceptive angiogenesis
GO:0003181 atrioventricular valve morphogenesis
GO:0003278 apoptosis involved in heart morphogenesis
GO:0003281 ventricular septum development
GO:0005576 extracellular region
GO:0005178 integrin binding
GO:0005520 insulin-like growth factor binding
GO:0006800 oxygen and reactive oxygen species metabolic process
GO:0006935 chemotaxis
GO:0008201 heparin binding
GO:0010518 positive regulation of phospholipase activity
GO:0010811 positive regulation of cell-substrate adhesion
GO:0050840 extracellular matrix binding
GO:0030198 extracellular matrix organization
GO:0030335 positive regulation of cell migration
GO:0043065 positive regulation of apoptosis
GO:0043066 negative regulation of apoptosis
GO:0043280 positive regulation of caspase activity
GO:0045597 positive regulation of cell differentiation
GO:0051789 response to protein stimulus
GO:0060413 atrial septum morphogenesis
GO:0060591 chondroblast differentiation
GO:0060710 chorio-allantoic fusion
GO:0060716 labyrinthine layer blood vessel development
GO:0061036 positive regulation of cartilage development
GO:2000304 positive regulation of ceramide biosynthetic process
Regulatory
For research purposes only

Applications of CYR61 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 5 ug/ml
Western Blotting 0.5 4.0 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti CYR61 antibody recognizes a band of approximately 42 kDa in Jurkat cell lysate and mouse small intestine tissue lysates

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Sheep anti Rabbit IgG:Biotin 2AB02B 1 ml C E P WB
Goat anti Rabbit IgG (Fc):Biotin STAR121B 1 mg E WB
Goat anti Rabbit IgG (Fc):FITC STAR121F 1 mg F
Goat anti Rabbit IgG (Fc):HRP STAR121P 1 mg E WB
Goat anti Rabbit IgG (H/L):HRP STAR124P 1 mg C E WB
Sheep anti Rabbit IgG:FITC STAR34B 1 mg C F
Sheep anti Rabbit IgG:RPE STAR35A 1 ml F
Sheep anti Rabbit IgG:DyLight®488 STAR36D488GA 0.1 mg F IF WB
Sheep anti Rabbit IgG:DyLight®549 STAR36D549GA 0.1 mg F IF
Sheep anti Rabbit IgG:DyLight®649 STAR36D649GA 0.1 mg F IF
Sheep anti Rabbit IgG:DyLight®680 STAR36D680GA 0.1 mg F IF WB
Sheep anti Rabbit IgG:Dylight®800 STAR36D800GA 0.1 mg F IF WB