CXXC4 antibody

Rabbit anti Mouse CXXC4

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
CXXC4

Product Code Applications Pack Size List Price Your Price Qty
AHP3036
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 0.1 ml loader
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loader
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Rabbit anti Mouse CXXC4 antibody recognizes CXXC finger protein 4, also known as inhibition of the DVL and axin complex protein.

CXXC4 is a 36 kDa protein that acts as a negative regulator of the Wnt signaling pathway through its interaction with dishevelled (DVL1). CXXC4 is thought to regulate DNA demethylation. Inhibition of CXXC4 has been linked to various cancers, including malignant renal cell carcinoma (Kojima et al. 2009).

Target Species
Mouse
Species Cross-Reactivity
Target SpeciesCross Reactivity
Human
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to mouse CXXC4 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.035% Sodium Azide (NaN3)
30% Glycerol
Carrier Free
Yes
Immunogen
A peptide within the N-terminal region of mouse CXXC4
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000 1/2500
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
Q6NXI8
Entrez Gene
Cxxc4
GO Terms
GO:0003677 DNA binding
GO:0016055 Wnt receptor signaling pathway
GO:0008270 zinc ion binding
GO:0016023 cytoplasmic membrane-bounded vesicle
Request a different product with this specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Mouse Products