OAS1 antibody

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Goat anti OAS1

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product Code Applications Pack Size List Price Quantity
AHP3023
Datasheet
WB
SDS
0.1 mg

Goat anti OAS1 antibody recognizes 2'-5'-oligoadenylate synthase 1 (OAS1), also known as E18/E16 and p46/p42 OAS.

OAS1 is a member of the OAS family of genes induced by interferons (IFN) and viruses, and appears to play a role in regulation of signaling pathways during viral infection (Lee et al. 2019). The antiviral role of OAS1 appears to be attributed to its ability to detect short double stranded RNAs (dsRNAs) (Schwartz et al. 2020). In addition to viral infections, OAS proteins have been implicated in autoimmune diseases and cancer. OAS1 can affect cell migration and high OAS1 mRNA expression has been linked to worse prognosis in patients with breast cancer (Zhang and Yu 2020).

Product Details

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antisera to human OAS1 were raised by repeated immunizations of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution
TRIS buffered saline
Preservative Stabilisers
0.02% Sodium Azide
0.5% Bovine Serum Albumin
Immunogen
Peptide with sequence C-THEYPHFSHRPST, from the internal region (near C terminus) of the protein sequence according to NP_058132.2
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee
12 months from date of despatch

More Information

UniProt
P00973
Entrez Gene
OAS1
Regulatory
For research purposes only

Applications of OAS1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1 ug/ml 3 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Goat anti Human OAS1 antibody detects a band of approximately 50 kDa in cell lysates

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Rabbit anti Goat IgG (Fc):FITC STAR122F F 1 mg loader
Rabbit anti Goat IgG (Fc):HRP STAR122P C E WB 1 mg loader

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