DPF2 antibody

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Goat anti DPF2

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product Code Applications Pack Size List Price Quantity
AHP3020
Datasheet
P WB
SDS
0.1 mg

Goat anti DPF2 antibody recognizes zinc finger protein ubi-d4, also known as BAF45D, REQ, and UBID4.

DPF2 is a plant homeodomain (PHD) finger protein with roles in apoptosis, noncanonical NF-kappaB signaling and oncogenesis (Liu et al. 2015). It acts as an adaptor protein, linking RelB/p52 with the SWI/SNF chromatin-remodeling complex (Shin et al. 2017). In human tissues, DPF2 is ubiquitously expressed but was discovered as being required for apoptosis in myeloid cells. Furthermore, this protein appears to play a role in inhibiting the differentiation of myeloid cells. DPF2 is associated with multiple human cancers including cervical cancer and acute myelogenous leukemia (AML) (Huber et al. 2017). DPF2 also appears to play a role in influenza infection, with knockdown of DPF2 leading to decreased infectivity of the virus (Shin et al. 2017).

Product Details

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antisera to human DPF2 were raised by repeated immunizations of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution
TRIS buffered saline
Preservative Stabilisers
0.02% Sodium Azide
0.5% Bovine Serum Albumin
Immunogen
Peptide with sequence C-QPPTPVSQRSEEQKS, from the internal region of the protein sequence according to NP_006259.1
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee
12 months from date of despatch

More Information

UniProt
Q92785
Entrez Gene
DPF2
GO Terms
GO:0003676 nucleic acid binding
GO:0006915 apoptosis
GO:0005634 nucleus
GO:0005813 centrosome
GO:0006350 transcription
GO:0008270 zinc ion binding
GO:0008624 induction of apoptosis by extracellular signals
GO:0045449 regulation of transcription
Regulatory
For research purposes only

Applications of DPF2 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 5 ug/ml
Western Blotting 1 ug/ml 3 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Goat anti Human DPF2 antibody detects a band of approximately 50 kDa and 48 kDa in cell lysates

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Rabbit anti Goat IgG (Fc):FITC STAR122F F 1 mg loader
Rabbit anti Goat IgG (Fc):HRP STAR122P C E WB 1 mg loader

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