Chromogranin A antibody
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WB ResetSheep anti Human Chromogranin A
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- Chromogranin A
Antibody Quality and 
Unrivaled 
| Sheep anti Human Chromogranin antibodyrecognizes human chromogranin A, a secreted peptide that inhibits glucose-induced insulin release. Chromogranin A is an activator of microglia (Taupenaut et al. 1996) and is notably upregulated and prominantly expressed in the senile plaques associated with Alzheimer's disease (Yasuhara et al. 1994). |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Bovine Expected from Sequence Chimpanzee Expected from Sequence Dog Expected from Sequence Horse Expected from Sequence Pig Expected from Sequence Mouse Expected from Sequence Rat Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- Synthetic peptide corresponding to the amino acids 1 - 15 (lpvnspmnkgdtevm) of the native molecule conjugated to Keyhole limpet Haemocyanin.
- Approx. Protein Concentrations
- IgG concentration 5.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
||
| Immunohistology - Paraffin 1 | |
1/25 | 1/100 |
- 1This product requires protein digestion pre-treatment of paraffin sections. Pronase is recommended for this purpose.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Histology Positive Control Tissue
- Human pancreas
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- RRID
- AB_2260642
- UniProt
- P10645
- Entrez Gene
- CHGA
- GO Terms
- GO:0005576 extracellular region
- GO:0008217 regulation of blood pressure
View more products with Chromogranin A specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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