Androgen Receptor antibody

ISO 9001 Quality Assurance Manufacturing | Print

Anti Androgen Receptor Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with androgen receptor antibody followed by detection with HRP conjugated Rabbit anti Goat IgG (Fc) (1/50,000, STAR122P) and visualized on the ChemiDoc MP with 77 second exposure. Arrow points to androgen receptor (molecular weight 110 kDa)

Filter by Application:

Goat anti Androgen Receptor

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: Androgen Receptor

Quick Links:

Secondary Antibodies
Applications
Storage Information
Batch/Lot Specific Datasheets

Antibody Quality and Performance Guarantee

Unrivaled Technical Support

Product Code Applications Pack Size List Price Your Price Qty

List Price	Your Price
VPA00046 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
	Log in

Goat anti Human androgen receptor antibody recognizes the human androgen receptor (AR), also known as the dihydrotestosterone receptor or nuclear receptor subfamily 3 group C member 4. AR is a ligand-activated transcription factor that belongs to a large family of nuclear receptor proteins. Unbound AR resides predominately in the cytoplasm as a heteromeric complex with hsp90 and other chaperone proteins. These chaperone proteins maintain AR in a form that is receptive to ligand binding. Upon ligand binding, AR recruits a variety of factors including coactivators and mediator proteins whose enzymatic activities promote chromatin remodeling and transcriptional regulation of target genes leading to cell differentiation, survival, and proliferation.

Mutated AR is strongly implicated in development of prostate adenocarcinoma and metastases development.

Goat anti Human androgen receptor antibody recognizes androgen receptor as a single band of approximately 110 kDa in LNCaP cell lysates by western blotting under reducing conditions.

Target Species: Human
Western Blotting: Goat anti androgen receptor detects a band of approximately 110 kDa in LNCaP cell lysates.
Product Form: Purified IgG - liquid
Preparation: Goat polyclonal antibody purified by affinity chromatography.
Buffer Solution: TRIS buffered saline.
Preservative Stabilisers: 0.02% Sodium Azide (NaN₃)
0.5% Bovine Serum Albumin
Immunogen: Peptide with sequence EVQLGLGRVYPRPPSC from the N-terminus of the androgen receptor.
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Rabbit anti Goat IgG (Fc):HRP	STAR122P	C E WB	1 mg	Log in	Get Quote
List Price	Your Price
	Log in
Description	Rabbit anti Goat IgG (Fc):HRP

UniProt: P10275
Entrez Gene: AR
GO Terms: GO:0016049 cell growth; GO:0003700 sequence-specific DNA binding transcription factor activity; GO:0005102 receptor binding; GO:0004882 androgen receptor activity; GO:0005497 androgen binding; GO:0005737 cytoplasm; GO:0005654 nucleoplasm; GO:0006810 transport; GO:0007267 cell-cell signaling; View More GO Terms; GO:0008013 beta-catenin binding; GO:0008134 transcription factor binding; GO:0008219 cell death; GO:0008270 zinc ion binding; GO:0008283 cell proliferation; GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter; GO:0010843 promoter binding; GO:0016563 transcription activator activity; GO:0019899 enzyme binding; GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor; GO:0046983 protein dimerization activity