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CXCL9 antibody

Product Code Applications Pack Size List Price Your Price Qty
AHP2369
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E WB 0.1 mg loader
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loader

Rabbit anti Bovine CXCL9 polyclonal antibody recognizes bovine CXCL9, otherwise known as MIG (monokine induced by Interferon-gamma). CXCL9 is a member of the C-X-C family of chemokine receptors, secreted by interferonγ stimulated monocytes, macrophages (Muller et al. 2010) and endothelial cells (Loos et al. 2006).

CXCL9 acts as a Th1 (type 1 helper T) cell chemoattractant, and plays a role in the growth, activation and movement of cells associated with, and in, tumor growth inhibition and angiogenesis (Whiting et al. 2004).

Target Species
Bovine
Product Form
Purified IgG - liquid
Antiserum Preparation
Antisera to bovine CXCL9 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Recombinant bovine CXCL9
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1.0 ug/ml 10 ug/ml
Western Blotting 0.1 ug/ml 1.0 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
ELISA
This product may be used as a capture antibody in a sandwich ELISA together with AHP2369B as the detection reagent. Recombinant Bovine CXCL9 (PBP023) may be used as a standard.

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Goat anti Rabbit IgG (Fc):Biotin STAR121B E WB 1 mg loader
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Description Goat anti Rabbit IgG (Fc):Biotin
Goat anti Rabbit IgG (Fc):FITC STAR121F F 1 mg loader
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Description Goat anti Rabbit IgG (Fc):FITC
Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
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Description Goat anti Rabbit IgG (Fc):HRP
Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
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Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader
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Description Sheep anti Rabbit IgG:RPE

Description Product Code Applications Pack Size List Price Your Price Quantity
Rabbit anti Bovine CXCL9:Biotin AHP2369B E WB 50 µg loader
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loader
Description Rabbit anti Bovine CXCL9:Biotin
Recombinant Bovine CXCL9 PBP023 E 5 µg loader
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Description Recombinant Bovine CXCL9

Further Reading

  1. Müller, M. et al. (2010) Review: The chemokine receptor CXCR3 and its ligands CXCL9, CXCL10 and CXCL11 in neuroimmunity--a tale of conflict and conundrum.
    Neuropathol Appl Neurobiol. 36: 368-87.
  2. Whiting, D. et al. (2004) Chemokine monokine induced by IFN-gamma/CXC chemokine ligand 9 stimulates T lymphocyte proliferation and effector cytokine production.
    J Immunol. 172: 7417-24.
  3. Loos, T. et al. (2006) TLR ligands and cytokines induce CXCR3 ligands in endothelial cells: enhanced CXCL9 in autoimmune arthritis.
    Lab Invest. 86: 902-16.

Synonyms
MIG
UniProt
A9QWP9
Entrez Gene
CXCL9
GO Terms
GO:0005615 extracellular space
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0008009 chemokine activity

AHP2369

151210 162426 164736

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