Asialofetuin antibody

Sheep anti Bovine Asialofetuin

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Asialofetuin

Product Code Applications Pack Size List Price Your Price Qty
0754-8050
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E 1 ml
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Sheep anti Bovine asialofetuin antibody recognizes bovine Alpha-2-HS-glycoprotein, also known as asialofetuin or fetuin-A. Asialofetuin is a 359 amino acid ~55kDa secreted glycoprotein containing two cystatin fetuin-A-type domains.

Asialofetuin is produced in the liver and bone marrow and acts as a negative acute-phase protein attenuating the inflammatory response to acute injury (Wang et al. 2010).

In a simple antigen down ELISA, Sheep anti Bovine asialofetuin antibody reacts with:
asialofetuin (ab at 1/8000) 100%
fetuin (ab at 1/2000) 100%
fetuin (ab at 1/8000) 50%

Target Species
Bovine
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Native
Approx. Protein Concentrations
IgG concentration 5.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/1000 1/4000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

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References for Asialofetuin antibody

  1. Blome, M.C. et al. (2010) Surface plasmon resonance analysis of ricin binding to plasma membranes isolated from NIH 3T3 cells.
    Anal Biochem. 396: 212-6.
  2. Bayer, H. et al. (2012) Evaluation of riproximin binding properties reveals a novel mechanism for cellular targeting.
    J Biol Chem. 287 (43): 35873-86.

RRID
AB_616939
UniProt
P12763
Entrez Gene
AHSG
GO Terms
GO:0006953 acute-phase response
GO:0005576 extracellular region
GO:0004869 cysteine-type endopeptidase inhibitor activity
GO:0030502 negative regulation of bone mineralization
GO:0050727 regulation of inflammatory response
GO:0050766 positive regulation of phagocytosis
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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