Tetanus Exotoxin antibody

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Goat anti Clostridium tetani Tetanus Exotoxin

Product Type: Polyclonal Antibody
Isotype: Polyclonal IgG

Product Code	Applications	Datasheet	MSDS	Pack Size	List Price	Quantity
8750-2059G	E WB			1 ml

Goat anti tetanus exotoxin antibody recognizes tetanus toxin, also known as tentoxylysin, produced by the soil micro-organism Clostridium tetani. Infection by Clostridium tetani. results in its systemic growth and secretion of tetanus toxin which causes muscle spasms by inhibiting neurotransmitter release.

Goat anti tetanus exotoxin antibody also reacts with the C-fragment (~50 kDa carboxy terminal residues 865-1315) of tetanus toxin (Emsley et al. 2000).

Product Details

Target Species

Bacterial

Product Form

Purified IgG - liquid

Antiserum Preparation

Antisera to C.Tetani Exotoxin were raised by repeated immunisations of goat with highly purified antigen. Purified IgG prepared by affinity chromatography.

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

0.09%

Sodium Azide (NaN₃)

Immunogen

Tetanus Exotoxin.

Approx. Protein Concentrations

IgG concentration 5.0mg/ml

Storage Information

Storage: Store at +4^oC or at -20^oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

More Information

UniProt: P04958 Related reagents
GO Terms: GO:0004222 metalloendopeptidase activity; GO:0005576 extracellular region; GO:0006508 proteolysis; GO:0008270 zinc ion binding; GO:0009405 pathogenesis; GO:0050827 toxin receptor binding; GO:0051609 inhibition of neurotransmitter uptake
Regulatory: For research purposes only

Applications of Tetanus Exotoxin antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
ELISA			1ug/ml
Western Blotting		1/100	1/500

Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Secondary Antibodies Available

Description	Product Code	Pack Size	Applications	List Price	Quantity
Rabbit anti Goat IgG (Fc):FITC	STAR122F	1 mg	F
Rabbit anti Goat IgG (Fc):HRP	STAR122P	1 mg	C E WB

Product Specific References

References for Tetanus Exotoxin antibody

Paillot, R.et al. (2015) ISCOM-based equine influenza vaccine: Duration of immunity and randomised clinical trials to assess an accelerated schedule of immunisation and efficacy
Trials in Vaccinology. 4: 61-70.