Goat anti tetanus exotoxin antibody
recognizes tetanus toxin, also known as tentoxylysin, produced by the soil micro-organism Clostridium tetani.
Infection by Clostridium tetani.
results in its systemic growth and secretion of tetanus toxin which causes muscle spasms by inhibiting neurotransmitter release.
Goat anti tetanus exotoxin antibody also reacts with the C-fragment (~50 kDa carboxy terminal residues 865-1315) of tetanus toxin (Emsley et al. 2000
- Target Species
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to C.Tetani Exotoxin were raised by repeated immunisations of goat with highly purified antigen. Purified IgG prepared by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- Tetanus Exotoxin.
- Approx. Protein Concentrations
- IgG concentration 5.0mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- GO Terms
zinc ion binding
toxin receptor binding
inhibition of neurotransmitter uptake
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Tetanus Exotoxin antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Copyright © 2020 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
Product Specific References
References for Tetanus Exotoxin antibody
Paillot, R.et al. (2015) ISCOM-based equine influenza vaccine: Duration of immunity and randomised clinical trials to assess an accelerated schedule of immunisation and efficacy
Trials in Vaccinology. 4: 61-70.
Cook, T.M. et al. (2001) Tetanus: a review of the literature.
Br J Anaesth. 87 (3): 477-87.