Tetanus Exotoxin antibody
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Goat anti tetanus exotoxin antibody recognizes tetanus toxin, also known as tentoxylysin, produced by the soil micro-organism Clostridium tetani. Infection by Clostridium tetani. results in its systemic growth and secretion of tetanus toxin which causes muscle spasms by inhibiting neurotransmitter release.
Goat anti tetanus exotoxin antibody also reacts with the C-fragment (~50 kDa carboxy terminal residues 865-1315) of tetanus toxin (Emsley et al. 2000).
Goat anti tetanus exotoxin antibody also reacts with the C-fragment (~50 kDa carboxy terminal residues 865-1315) of tetanus toxin (Emsley et al. 2000).
Product Details
- Target Species
- Bacterial
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to C.Tetani Exotoxin were raised by repeated immunisations of goat with highly purified antigen. Purified IgG prepared by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide (NaN3) - Immunogen
- Tetanus Exotoxin.
- Approx. Protein Concentrations
- IgG concentration 5.0mg/ml
Storage Information
- Storage
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P04958
- GO Terms
- GO:0004222 metalloendopeptidase activity
- GO:0005576 extracellular region
- GO:0006508 proteolysis
- GO:0008270 zinc ion binding
- GO:0009405 pathogenesis
- GO:0050827 toxin receptor binding
- GO:0051609 inhibition of neurotransmitter uptake
- Regulatory
- For research purposes only
Applications of Tetanus Exotoxin antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA | 1ug/ml | ||
| Western Blotting | 1/100 | 1/500 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Rabbit anti Goat IgG (Fc):FITC | STAR122F | F | 1 mg |
|
|
| Rabbit anti Goat IgG (Fc):HRP | STAR122P | C E WB | 1 mg |
|
Product Specific References
References for Tetanus Exotoxin antibody
-
Paillot, R.et al. (2015) ISCOM-based equine influenza vaccine: Duration of immunity and randomised clinical trials to assess an accelerated schedule of immunisation and efficacy
Trials in Vaccinology. 4: 61-70.
Further Reading
-
Cook, T.M. et al. (2001) Tetanus: a review of the literature.
Br J Anaesth. 87 (3): 477-87.
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