Fc Epsilon R1 Alpha antibody | MAR-1

Hamster anti Mouse Fc Epsilon R1 Alpha

Product Type
Monoclonal Antibody
Clone
MAR-1
Isotype
IgG
Specificity
Fc Epsilon R1 Alpha

Product Code Applications Pack Size List Price Your Price Qty
MCA6066GA
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
F 0.1 mg loader
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loader
Search for Batch Specific Datasheets

Hamster anti mouse Fc epsilon R1 alpha, clone MAR-1 recognizes Fc receptor epsilon R1 alpha also known as FceRIalpha or high affinity IgE receptor. The Fc epsilon R1 complex is involved in initiating IgE-mediated allergic reactions. Fc receptor epsilon is primarily expressed on mast cells and basophils. Activation of Fc epsilon R1 leads to release of allergic mediators such as histamine.

Target Species
Mouse
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
<0.1% Sodium Azide (NaN3)
Immunogen
Mouse Fc epsilon receptor alpha subunit
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry 1/20 1/80
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Flow Cytometry
Use 10 μl of the suggested working dilution to label 1x106 cells in 100ul

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UniProt
P20489
Entrez Gene
Fcer1a
GO Terms
GO:0001812 positive regulation of type I hypersensitivity
GO:0001820 serotonin secretion
GO:0005887 integral to plasma membrane
GO:0007166 cell surface receptor linked signaling pathway
GO:0007257 activation of JUN kinase activity
GO:0009897 external side of plasma membrane
GO:0019370 leukotriene biosynthetic process
GO:0019767 IgE receptor activity
GO:0043306 positive regulation of mast cell degranulation
GO:0045121 membrane raft
GO:0045401 positive regulation of interleukin-3 biosynthetic process
GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050850 positive regulation of calcium-mediated signaling
View more products with FC EPSILON R1 ALPHA specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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