Transferrin antibody | 14C10

Mouse anti Transferrin

Product Type
PrecisionAb Monoclonal
Clone
14C10
Isotype
IgG1
Format
Purified
Specificity
Transferrin

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VMA00578
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Mouse anti Human transferrin antibody recognizes serotransferrin, also known as beta-1 metal-binding globulin or siderophilin.

The TF gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum (provided by RefSeq, Sep 2009).

Mouse anti Human transferrin antibody detects a band of 83 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti transferrin detects a band of approximately 83 kDa in HepG2 cell lysates.
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography on Protein G from ascites.
Buffer Solution
HEPES buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
<50% Glycerol
Immunogen
Transferrin purified from human plasma
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml loader
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Description Goat anti Mouse IgG (H/L):HRP

UniProt
P02787
Entrez Gene
TF
GO Terms
GO:0002576 platelet degranulation
GO:0005576 extracellular region
GO:0005769 early endosome
GO:0005770 late endosome
GO:0030141 stored secretory granule
GO:0030139 endocytic vesicle
GO:0005905 coated pit
GO:0006879 cellular iron ion homeostasis
GO:0008199 ferric iron binding
GO:0009925 basal plasma membrane
GO:0010008 endosome membrane
GO:0016324 apical plasma membrane
GO:0030168 platelet activation
GO:0033572 transferrin transport
GO:0048471 perinuclear region of cytoplasm
GO:0055037 recycling endosome
GO:0055085 transmembrane transport
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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