TMEM173 antibody | OTI4H1

Mouse anti TMEM173

Product Type
PrecisionAb Monoclonal
Clone
OTI4H1
Isotype
IgG2a
Format
Purified
Specificity
TMEM173

Product Code Applications Pack Size List Price Your Price Qty
VMA00456
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl loader
List Price Your Price
loader
Search for Batch Specific Datasheets

Mouse anti Human TMEM173 antibody, clone OTI4H1 recognizes TMEM173, also known as N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, endoplasmic reticulum interferon stimulator, mitochondrial mediator of IRF3 activation or STING. Mutations in the TMEM173 gene have been associated with the development of STING-associated vasculopathy with onset in infancy (SAVI) an autoinflammatory vasculopathy characterized by early onset inflammation leading to severe skin associated lesions.

Mouse anti Human TMEM173 antibody, clone OTI4H1 detects a band of 37 kDa.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti TMEM173 detects a band of approximately 37 kDa in THP-1 cell lysate.
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G from ascites.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
50% Glycerol
Immunogen
Full length recombinant protein of human TMEM173 produced in HEK293T
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml.
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description Product Code Applications Pack Size List Price Your Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml loader
List Price Your Price
loader
Description Goat anti Mouse IgG (H/L):HRP

Synonyms
Sting
UniProt
Q86WV6
Entrez Gene
TMEM173
GO Terms
GO:0005886 plasma membrane
GO:0006915 apoptosis
GO:0016021 integral to membrane
GO:0005741 mitochondrial outer membrane
GO:0005789 endoplasmic reticulum membrane
GO:0019901 protein kinase binding
GO:0032608 interferon-beta production
GO:0042803 protein homodimerization activity
GO:0045087 innate immune response
GO:0048471 perinuclear region of cytoplasm
GO:0051607 defense response to virus
Request a different product with this specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products