TMEM173 antibody | OTI4H1

100% Secure

Mouse anti TMEM173

Product Type
PrecisionAb Monoclonal
Product Code Applications Pack Size List Price Quantity
100 µl loader

Mouse anti Human TMEM173 antibody, clone OTI4H1 recognizes TMEM173, also known as N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, endoplasmic reticulum interferon stimulator, mitochondrial mediator of IRF3 activation or STING. Mutations in the TMEM173 gene have been associated with the development of STING-associated vasculopathy with onset in infancy (SAVI) an autoinflammatory vasculopathy characterized by early onset inflammation leading to severe skin associated lesions.

Mouse anti Human TMEM173 antibody, clone OTI4H1 detects a band of 37 kDa.

Product Details

Target Species
Western Blotting
Anti TMEM173 detects a band of approximately 37 kDa in THP-1 cell lysate
Product Form
Purified IgG - liquid
Purified IgG prepared by affinity chromatography on Protein G from ascites
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
50% Glycerol
Full length recombinant protein of human TMEM173 produced in HEK293T
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml

Storage Information

Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
12 months from date of despatch

More Information

Entrez Gene
GO Terms
GO:0005886 plasma membrane
GO:0006915 apoptosis
GO:0016021 integral to membrane
GO:0005741 mitochondrial outer membrane
GO:0005789 endoplasmic reticulum membrane
GO:0019901 protein kinase binding
GO:0032608 interferon-beta production
GO:0042803 protein homodimerization activity
GO:0045087 innate immune response
GO:0048471 perinuclear region of cytoplasm
GO:0051607 defense response to virus
PrecisionAb is a trademark of Bio-Rad Laboratories.
For research purposes only

Applications of TMEM173 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml

Fluorescent Spectraviewer

Watch the Tool Tutorial Video ▸

How to Use the Spectraviewer

Watch the Tool Tutorial Video ▸
  • Start by selecting the application you are interested in, with the option to select an instrument from the drop down menu or create a customized instrument
  • Select the fluorophores or fluorescent proteins you want to include in your panel to check compatibility
  • Select the lasers and filters you wish to include
  • Select combined or multi-laser view to visualize the spectra