STAT5 antibody | OTI9F7

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Anti STAT5 Antibody, clone OTI9F7 (PrecisionAb Monoclonal Antibody) thumbnail image 1

Anti STAT5 Antibody, clone OTI9F7 (PrecisionAb Monoclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with STAT5 antibody followed by detection with HRP conjugated Goat anti Mouse IgG (1/10,000, STAR207P) and visualized on the ChemiDoc MP with 9 second exposure. Arrow points to STAT5 (molecular weight 90 kDa)

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Mouse anti STAT5

Product Type: PrecisionAb Monoclonal
Clone: OTI9F7
Isotype: IgG1
Format: Purified
Specificity: STAT5

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VMA00711 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Mouse anti Human STAT5 antibody recognizes the signal transducer and activator of transcription 5A/5B.

Signal transducer and activator of transcription 5 (STAT5) refers to two highly related proteins, STAT5A and STAT5B, which are part of the STAT family of transcription factors. In response to cytokines (IL2, IL4) and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. It has been shown that STAT5 is involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. Though STAT5A and STAT5B are encoded by separate genes, the proteins are 90% identical at the amino acid level. Aberrant STAT5 activity has been shown to be closely connected to a wide range of human cancers (provided by RefSeq, Jul 2008).

Mouse anti Human STAT5 detects a band of 90 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Mouse anti STAT5 detects a band of approximately 90 kDa in K562 cell lysates
Product Form: Purified IgG - Liquid
Preparation: Mouse monoclonal antibody affinity purified on Protein G from ascites
Buffer Solution: Phosphate buffered saline
Preservative Stabilisers: 0.09% Sodium Azide
1% Bovine Serum Albumin
<50% Glycerol
Immunogen: Full length recombinant human STAT5A produced in HEK293T cells
Regulatory: For research purposes only
Guarantee: 12 months from date of despatch
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Mouse IgG (H/L):HRP	STAR207P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Mouse IgG (H/L):HRP

UniProt: P42229; P51692
Entrez Gene: STAT5A; STAT5B
GO Terms: GO:0005515 protein binding; GO:0000255 allantoin metabolic process; GO:0005509 calcium ion binding; GO:0003677 DNA binding; GO:0003700 sequence-specific DNA binding transcription factor activity; GO:0005829 cytosol; GO:0005654 nucleoplasm; GO:0006101 citrate metabolic process; GO:0006103 2-oxoglutarate metabolic process; View More GO Terms; GO:0006105 succinate metabolic process; GO:0006107 oxaloacetate metabolic process; GO:0006549 isoleucine metabolic process; GO:0006573 valine metabolic process; GO:0006600 creatine metabolic process; GO:0006631 fatty acid metabolic process; GO:0019530 taurine metabolic process; GO:0046449 creatinine metabolic process; GO:0032355 response to estradiol stimulus; GO:0035259 glucocorticoid receptor binding; GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway