STAT5 antibody | OTI9F7
Filter by Application:
WB ResetMouse anti STAT5
- Product Type
- PrecisionAb Monoclonal
- Clone
- OTI9F7
- Isotype
- IgG1
- Format
- Purified
- Specificity
- STAT5
Quick Links:
Antibody Quality and 
Unrivaled 
| Mouse anti Human STAT5 antibody recognizes the signal transducer and activator of transcription 5A/5B. Signal transducer and activator of transcription 5 (STAT5) refers to two highly related proteins, STAT5A and STAT5B, which are part of the STAT family of transcription factors. In response to cytokines (IL2, IL4) and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. It has been shown that STAT5 is involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. Though STAT5A and STAT5B are encoded by separate genes, the proteins are 90% identical at the amino acid level. Aberrant STAT5 activity has been shown to be closely connected to a wide range of human cancers (provided by RefSeq, Jul 2008). Mouse anti Human STAT5 detects a band of 90 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
|
- Target Species
- Human
- Western Blotting
- Mouse anti STAT5 detects a band of approximately 90 kDa in K562 cell lysates
- Product Form
- Purified IgG - Liquid
- Preparation
- Mouse monoclonal antibody affinity purified on Protein G from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
1% Bovine Serum Albumin
<50% Glycerol - Immunogen
- Full length recombinant human STAT5A produced in HEK293T cells
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
 |
Log in | ||
| List Price | Your Price | ||||||
|
|
Log in | ||||||
| Description | Goat anti Mouse IgG (H/L):HRP | ||||||
- UniProt
- P42229
- P51692
- Entrez Gene
- STAT5A
- STAT5B
- GO Terms
- GO:0005515 protein binding
- GO:0000255 allantoin metabolic process
- GO:0005509 calcium ion binding
- GO:0003677 DNA binding
- GO:0003700 sequence-specific DNA binding transcription factor activity
- GO:0005829 cytosol
- GO:0005654 nucleoplasm
- GO:0006101 citrate metabolic process
- GO:0006103 2-oxoglutarate metabolic process
- View More GO Terms
- GO:0006105 succinate metabolic process
- GO:0006107 oxaloacetate metabolic process
- GO:0006549 isoleucine metabolic process
- GO:0006573 valine metabolic process
- GO:0006600 creatine metabolic process
- GO:0006631 fatty acid metabolic process
- GO:0019530 taurine metabolic process
- GO:0046449 creatinine metabolic process
- GO:0032355 response to estradiol stimulus
- GO:0035259 glucocorticoid receptor binding
- GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway
View more products with STAT5 specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
View all Anti-Human ProductsAlways be the first to know.
When we launch new products and resources to help you achieve more in the lab.
Yes, sign me up