Somatostatin antibody | YC7
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|Rat anti Human Somatostatin antibody, clone YC7 recognizes somatostatin, a hormone involved in endocrine system regulation through interactions with pituitary growth hormone, thyroid stimulating hormone, and a number of hormones of the gastrointestinal tract. Somatostatin has active 14 amino acid and 28 amino acid forms, produced by alternate cleavage of the gene product.
This antibody does not cross react with enkephalins, other endorphins, substance P, or CGRP. It partially cross reacts with somatostatin fragments.
The epitope recognized by this antibody lies within the 1-14 amino acid sequence of cyclic somatostatin.
- Target Species
- Species Cross-Reactivity
Target Species Cross Reactivity Rat Guinea Pig Pig Mouse Zebrafish
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Tissue Culture Supernatant - liquid
- Preservative Stabilisers
- 0.05% Thiomersal
- Somatostatin conjugated to thyroglobulin.
- Fusion Partners
- Spleen cells from rats immunised with somatostatin conjugated to thyroglobulin were fused with a rat myeloma cell line.
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Frozen|
|Immunohistology - Paraffin|
References for Somatostatin antibody
Pidsudko, Z. et al. (2004) Distribution and chemical coding of neurons in intramural ganglia of the porcine urinary bladder trigone.
Folia Histochem Cytobiol. 42: 3-11.
Van Nassauw, L. et al. (2002) Neurochemical identification of enteric neurons expressing P2X(3) receptors in the guinea-pig ileum.
Histochem Cell Biol. 118 (3): 193-203.
Geuens, E. et al. (2003) A globin in the nucleus!
J Biol Chem. 278: 30417-20.
Kaleczyc, J. et al. (2002) Distribution, immunohistochemical characteristics and nerve pathways of primary sensory neurons supplying the porcine vas deferens.
Cell Tissue Res. 310: 9-17.
Pidsudko, Z. (2014) Immunohistochemical characteristics and distribution of sensory dorsal root Ganglia neurons supplying the urinary bladder in the male pig.
J Mol Neurosci. 52 (1): 71-81.
Hens, J. et al. (2001) Morphological and neurochemical identification of enteric neurones with mucosal projections in the human small intestine.
J Neurochem. 76: 464-71.
Hens, J. et al. (2000) Mucosal projections of enteric neurons in the porcine small intestine.
J Comp Neurol. 421: 429-36.
Rychlik, A. et al. (2002) Diarrhea-Induced Changes in Chemical Phenotypes of Enteric Structures in the Pig are not Sufficient to Discriminate between the Viral and Bacterial Etiology of the Disease.
Bull Vet Inst Pulawy 46, 187-96.
View The Latest Product References
Podlasz, P. et al. (2016) Galanin regulates blood glucose level in the zebrafish: a morphological and functional study.
Histochem Cell Biol. 145 (1): 105-17.
Kaleczyc, J. et al. (2007) The distribution and chemical coding of intramural neurons supplying the porcine stomach - the study on normal pigs and on animals suffering from swine dysentery.
Anat Histol Embryol. 36 (3): 186-93.
Pidsudko, Z. et al. (2008) Distribution and chemical coding of intramural neurons in the porcine ileum during proliferative enteropathy.
J Comp Pathol. 138 (1): 23-31.
Zacharko-Siembida, A. et al. (2017) An Immunohistochemical Study of Cocaine- and Amphetamine-Regulated Transcript (Cart) Expression in the Pterygopalatine Ganglion of the Pig.
Acta Veterinaria. 67 (3): 397-408.
Palus, K. et al. (2018) Neurochemical characteristics of calbindin-like immunoreactive coeliac-cranial mesenteric ganglion complex (CCMG) neurons supplying the pre-pyloric region of the porcine stomach
Tissue and Cell. 50: 8-14.
Milstein, C. & Cuello, A.C. (1983) Hybrid hybridomas and their use in immunohistochemistry.
Nature. 305: 537-40.
- Entrez Gene
- GO Terms
- GO:0005179 hormone activity
- GO:0005615 extracellular space
- GO:0007186 G-protein coupled receptor protein signaling pathway
- GO:0007268 synaptic transmission
- GO:0007584 response to nutrient
- GO:0007586 digestion
- GO:0008285 negative regulation of cell proliferation
- GO:0008628 induction of apoptosis by hormones
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